Intervertebral disc degeneration (IDD) is caused by genetics, aging, and environmental
factors and is one of the leading causes of low back pain. The treatment of IDD presents …

Low back pain (LBP) is a common health issue worldwide with a huge economic burden on
healthcare systems. In the United States alone, the cost is estimated to be $100 billion each …

Study Design. A magnetic resonance imaging study of human cadaver spines. Objective. To
investigate associations between cartilage endplate (CEP) thickness and disc degeneration …

Background Despite exciting advances in regenerative medicine, cell‐based strategies for
treating degenerative disc disease remain in their infancy. To maximize the potential for …

Purpose The aims of the study were to introduce a classification scheme for endplate lesions
based on T2-weighted magnetic resonance imaging and to detect possible associations …

Damage at the intervertebral disc‐vertebra interface associates with back pain and disc
herniation. However, the structural and biomechanical properties of the disc‐vertebra …

Magnetic resonance (MR) imaging has been widely implemented as a non-invasive
modality to investigate musculoskeletal (MSK) tissue disease, injury, and pathology …

Geometry plays an important role in intervertebral disc (IVD) mechanics. Previous
computational studies have found a link between IVD geometry and stiffness. However, few …

Background The function of the endplate (EP) is the most important factor influencing
nutritional supply to the avascular intervertebral disc (IVD). It is desired to have a non …

The cartilaginous endplate (CEP) plays a pivotal role in facilitating the supply of nutrients
and, transport of metabolic waste, as well as providing mechanical support for the …