Isoprenoids are the output of the polymerization of five-carbon, branched isoprenic chains
derived from isopentenyl pyrophosphate (IPP) and its isomer, dimethylallyl pyrophosphate …

Liver disease, a major cause of global mortality, has been associated with dysbiosis of the
intestinal microbiota (bacteria, fungi, viruses, and other microbes). Studies have associated …

Plants of the genus Centaurea have been widely used as natural therapeutics in different
countries. This study investigated the antioxidant–structure activity relationship of eight …

In this study, the protective effects of the Ganoderma atrum polysaccharide (PSG-1) on
selected tissue (liver, spleen, kidneys and intestine) toxicity induced by acrylamide (AA) in …

Non-alcoholic fatty liver disease (NAFLD) is a common chronic hepatic disorder
characterized by hepatic lipid accumulation. This study explored the effect of betulin (BE), a …

Tongba, chhyang, nigar and raksi are popular traditional drinks served in Nepal, northern
and north eastern part of India and Tibetan plateau which are claimed as medicinal and …

We investigated the effect of an 11β-HSD1 inhibitor (H8) on hepatic steatosis and its
mechanism of action. Although H8, a curcumin derivative, has been shown to alleviate …

Chronic hyperglycemia increases the risk of liver damage. Oxidative stress and aberrant
inflammatory response are entangled in diabetes-associated liver injury. This study …

Arbutin is a glycosylated hydroquinone with antioxidant and anti-hyperglycemia effects.
However, its beneficial effects in type 2 diabetes (T2D) were not clarified. This study …

The current study investigated the effects of sinapic acid on high‐fat diet (HFD)‐induced lipid
metabolism and oxidative stress in male Syrian hamsters. Sinapic acid treatment …