Skin penetration and tissue permeation after topical administration of diclofenac

M Hagen, M Baker - Current medical research and opinion, 2017 - Taylor & Francis
Objective: Topical delivery of drugs is an alternative to oral administration, often with similar
efficacy but potentially a more favorable tolerability profile. However, topical formulations …

Formulation and performance evaluation of emulgel platform for combined skin delivery of curcumin and propolis

RS Dos Santos, J Bassi da Silva… - Pharmaceutical …, 2023 - Taylor & Francis
The environment can modify the physiology and body protective function of the skin.
Propolis (PRP) and curcumin (CUR) possess important antioxidant and antimicrobial …

Functional polymeric systems as delivery vehicles for methylene blue in photodynamic therapy

MV Junqueira, FB Borghi-Pangoni, SBS Ferreira… - Langmuir, 2016 - ACS Publications
Antibiotic-resistant microorganisms have become a global concern, and the search for
alternative therapies is very important. Photodynamic therapy (PDT) consists of the use of a …

Hydrogel increases diclofenac skin permeation and absorption

E Haltner‐Ukomadu, M Sacha… - … & drug disposition, 2019 - Wiley Online Library
Purpose Topical nonsteroidal anti‐inflammatory drug formulations are used commonly to
treat musculoskeletal pain and inflammation. Drug properties and formulation composition …

[HTML][HTML] Ex vivo transdermal absorption of a liposome formulation of diclofenac

M Sacha, L Faucon, E Hamon, I Ly… - Biomedicine & …, 2019 - Elsevier
Topical formulations of non-steroidal anti-inflammatory drugs are often used to provide
effective local drug concentration while limiting systemic exposure and associated adverse …

Rheology of Complex Topical Formulations: An Analytical Quality by Design Approach to Method Optimization and Validation

L Chiarentin, C Cardoso, M Miranda, C Vitorino - Pharmaceutics, 2023 - mdpi.com
Analytical method validation ensures that a method provides trustworthy information about a
particular sample when applied in accordance with the predefined protocol. According to …

Emulgels Containing Carbopol 934P and Different Vegetable Oils for Topical Propolis Delivery: Bioadhesion, Drug Release Profile, and Ex Vivo Skin Permeation …

R Said dos Santos, CF Vecchi, HC Rosseto… - AAPS …, 2020 - Springer
Topical administration can enable a more efficient therapy based on the improved
bioavailability and patient compliance. Wounds and infections can lead to modifications of …

Preparation and characterization of bioadhesive system containing hypericin for local photodynamic therapy

FB Borghi-Pangoni, MV Junqueira… - Photodiagnosis and …, 2017 - Elsevier
Hypericin (Hyp) is a natural photoactive pigment utilized in the treatment of different types of
cancer and antimicrobial inactivation using photodynamic therapy (PDT). Hyp is poorly …

Emulgels containing propolis and curcumin: The effect of type of vegetable oil, poly (acrylic acid) and bioactive agent on physicochemical stability, mechanical and …

R Said dos Santos, J Bassi da Silva, HC Rosseto… - Gels, 2021 - mdpi.com
Emulgels are obtained by the entrapment of an organic phase within a three-dimensional
network built by hydrophilic molecules. Polymers based on cross-linked poly (acrylic acid) …

Emulgel: an emerging approach towards effective topical drug delivery

P Pandey, N Minocha, N Vashist, R Shah… - Drug Delivery …, 2022 - ingentaconnect.com
Background: During the development of the new formulations, the hydrophobic drugs face
many problems leading to poor water solubility and problems related to bioavailability …