Mammalian ABC transporters in health and disease
P Borst, RO Elferink - Annual review of biochemistry, 2002 - annualreviews.org
▪ Abstract The ATP-binding cassette (ABC) transporters are a family of large proteins in
membranes and are able to transport a variety of compounds through membranes against …
membranes and are able to transport a variety of compounds through membranes against …
ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal
CH Choi - Cancer cell international, 2005 - Springer
One of the major problems related with anticancer chemotherapy is resistance against
anticancer drugs. The ATP-binding cassette (ABC) transporters are a family of transporter …
anticancer drugs. The ATP-binding cassette (ABC) transporters are a family of transporter …
Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition
Resistance to chemotherapy remains one of the most significant obstacles to successful
cancer treatment. While inhibiting drug efflux mediated by ATP-binding cassette (ABC) …
cancer treatment. While inhibiting drug efflux mediated by ATP-binding cassette (ABC) …
Applications of catalytic asymmetric sulfide oxidations to the syntheses of biologically active sulfoxides
Optically active sulfoxides are important compounds for medicinal and pharmaceutical
chemistry. Driven by the increasing demand for efficient, selective and environmentally …
chemistry. Driven by the increasing demand for efficient, selective and environmentally …
Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development
Human contains 49 ATP-binding cassette (ABC) transporter genes and the multidrug
resistance associated proteins (MRP1/ABCC1, MRP2/ABCC2, MRP3/ABCC3 …
resistance associated proteins (MRP1/ABCC1, MRP2/ABCC2, MRP3/ABCC3 …
Glial and myeloid heterogeneity in the brain tumour microenvironment
Brain cancers carry bleak prognoses, with therapeutic advances hel** only a minority of
patients over the past decade. The brain tumour microenvironment (TME) is highly …
patients over the past decade. The brain tumour microenvironment (TME) is highly …
Monodentately-coordinated bioactive moieties in multimodal half-sandwich organoruthenium anticancer agents
Metallodrugs have a central role in the treatment and diagnosis of diseases. To overcome
potential toxicity and equip metal-based anticancer agents with biological activity, the choice …
potential toxicity and equip metal-based anticancer agents with biological activity, the choice …
Quinolones and non-steroidal anti-inflammatory drugs interacting with copper (II), nickel (II), cobalt (II) and zinc (II): structural features, biological evaluation and …
G Psomas, DP Kessissoglou - Dalton transactions, 2013 - pubs.rsc.org
The structural features of copper (II), nickel (II), cobalt (II) and zinc (II) complexes with the
antimicrobial drugs quinolones and non-steroidal anti-inflammatory drugs (NSAIDs) as …
antimicrobial drugs quinolones and non-steroidal anti-inflammatory drugs (NSAIDs) as …
Carrier-free nanodrug: A novel strategy of cancer diagnosis and synergistic therapy
MY Yang, RR Zhao, YF Fang, JL Jiang, XT Yuan… - International journal of …, 2019 - Elsevier
Nanoformulations with advantages in drug delivery, safety and pharmacodynamics have
been booming as a promising strategy for cancer therapy. However, the traditional …
been booming as a promising strategy for cancer therapy. However, the traditional …
Interaction of copper (II) with the non-steroidal anti-inflammatory drugs naproxen and diclofenac: Synthesis, structure, DNA-and albumin-binding
Copper (II) complexes with the non-steroidal anti-inflammatory drugs (NSAIDs) naproxen
and diclofenac have been synthesized and characterized in the presence of nitrogen donor …
and diclofenac have been synthesized and characterized in the presence of nitrogen donor …