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Smart contact lenses as wearable ophthalmic devices for disease monitoring and health management
The eye contains a complex network of physiological information and biomarkers for
monitoring disease and managing health, and ocular devices can be used to effectively …
monitoring disease and managing health, and ocular devices can be used to effectively …
[HTML][HTML] Immune responses to injury and their links to eye disease
MA Stepp, AS Menko - Translational Research, 2021 - Elsevier
The eye is regarded as an immune privileged site. Since the presence of a vasculature
would impair vision, the vasculature of the eye is located outside of the central light path. As …
would impair vision, the vasculature of the eye is located outside of the central light path. As …
[HTML][HTML] Drug delivery to the posterior segment of the eye: Biopharmaceutic and pharmacokinetic considerations
R Varela-Fernández, V Díaz-Tomé… - Pharmaceutics, 2020 - mdpi.com
The treatment of the posterior-segment ocular diseases, such as age-related eye diseases
(AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the …
(AMD) or diabetic retinopathy (DR), present a challenge for ophthalmologists due to the …
[HTML][HTML] Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …
tissues continues to be a key challenge for formulation scientists. Various attempts are …
[HTML][HTML] Pharmacokinetic aspects of retinal drug delivery
Drug delivery to the posterior eye segment is an important challenge in ophthalmology,
because many diseases affect the retina and choroid leading to impaired vision or …
because many diseases affect the retina and choroid leading to impaired vision or …
Design, clinical translation and immunological response of biomaterials in regenerative medicine
The field of regenerative medicine aims to replace tissues lost as a consequence of disease,
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …
trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative …
Biomarkers in diabetic retinopathy
There is a global diabetes epidemic correlating with an increase in obesity. This coincidence
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …
may lead to a rise in the prevalence of type 2 diabetes. There is also an as yet unexplained …
Human vitreous in proliferative diabetic retinopathy: characterization and translational implications
Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-
age population. DR is a progressive eye disease caused by long-term accumulation of …
age population. DR is a progressive eye disease caused by long-term accumulation of …
[HTML][HTML] Proteomic biomarkers of retinal inflammation in diabetic retinopathy
Diabetic retinopathy (DR), a sight-threatening neurovasculopathy, is the leading cause of
irreversible blindness in the developed world. DR arises as the result of prolonged …
irreversible blindness in the developed world. DR arises as the result of prolonged …
MALAT1: an epigenetic regulator of inflammation in diabetic retinopathy
Despite possessing limited protein-coding potential, long non-coding RNAs (lncRNAs) have
been implicated in a myriad of pathologic conditions. Most well documented in cancer, one …
been implicated in a myriad of pathologic conditions. Most well documented in cancer, one …