Balance is the dynamic and unconscious control of the body's centre of mass to maintain
postural equilibrium. Regulated by the vestibular system, head movement and acceleration …

Rehabilitative motor training is currently one of the most widely used approaches to promote
moderate recovery following injuries of the central nervous system. Such training is …

The pedunculopontine nucleus (PPN) is a locomotor command area containing
glutamatergic neurons that control locomotor initiation and maintenance. These motor …

In the current study we examined the effects of training in adult rats with a cervical spinal
cord injury (SCI). One group of rats received 6 weeks of training in a single pellet reaching …

A lateral hemisection injury of the cervical spinal cord results in Brown-Séquard syndrome in
humans and rats. The hands/forelimbs on the injured side are rendered permanently …

Smaller spinal cord injuries often allow some degree of spontaneous behavioral
improvements because of structural rearrangements within different descending fiber tracts …

Rodents are frequently used to model damage and diseases of the central nervous system
(CNS) that lead to functional deficits. Impaired locomotor function is currently evaluated by …

Stem cell therapy is a potential treatment for spinal cord injury and different stem cell types
have been grafted into animal models and humans suffering from spinal trauma. Due to …

Locomotor impairments after spinal cord injury (SCI) are often assessed using open-field
rating scales. These tasks have the advantage of spanning the range from complete …

The majority of animal studies examining the recovery of function following spinal cord injury
use the BBB Open-Field Locomotor Scale as a primary outcome measure. However, it is …