Cyclosporin A—a review on fermentative production, downstream processing and pharmacological applications

SA Survase, LD Kagliwal, US Annapure… - Biotechnology …, 2011 - Elsevier
In present times, the immunosuppressants have gained considerable importance in the
world market. Cyclosporin A (CyA) is a cyclic undecapeptide with a variety of biological …

Nonlinear least-squares data fitting in Excel spreadsheets

G Kemmer, S Keller - Nature protocols, 2010 - nature.com
We describe an intuitive and rapid procedure for analyzing experimental data by nonlinear
least-squares fitting (NLSF) in the most widely used spreadsheet program. Experimental …

Microbial acetylcholinesterase inhibitors for Alzheimer's therapy: recent trends on extraction, detection, irradiation-assisted production improvement and nano …

AG Zaki, ESR El-Sayed, M Abd Elkodous… - Applied Microbiology …, 2020 - Springer
Neurodegenerative disorders especially Alzheimer's disease (AD) are significantly
threatening the public health. Acetylcholinesterase (AChE) inhibitors are compounds of …

Production, Purification, and Characterization of Thermostable α‐Amylase Produced by Bacillus licheniformis Isolate AI20

YR Abdel-Fattah, NA Soliman… - Journal of …, 2013 - Wiley Online Library
An optimization strategy, based on statistical experimental design, is employed to enhance
the production of thermostable α‐amylase by a thermotolerant B. licheniformis AI20 isolate …

Production and enhancement of the acetylcholinesterase inhibitor, huperzine A, from an endophytic Alternaria brassicae AGF041

AG Zaki, EH El-Shatoury, AS Ahmed… - Applied microbiology and …, 2019 - Springer
Huperzine A (HupA) is a potent acetylcholinesterase (AChE) inhibitor of a great
consideration as a prospective drug candidate for Alzheimer's disease treatment. Production …

A review of algorithmic approaches for cell culture media optimization

T Zhou, R Reji, RS Kairon, KH Chiam - Frontiers in Bioengineering …, 2023 - frontiersin.org
Cell culture media composition and culture conditions play a crucial role in product yield,
quality and cost of production. Culture media optimization is the technique of improving …

Feather protein lysate optimization and feather meal formation using YNDH protease with keratinolytic activity afterward enzyme partial purification and …

DA Goda, AR Bassiouny, NM Abdel Monem… - Scientific Reports, 2021 - nature.com
Incubation parameters used for the creation of a protein lysate from enzymatically degraded
waste feathers using crude keratinase produced by the Laceyella sacchari strain YNDH …

Utilization of pretreated bagasse for the sustainable bioproduction of cellulase by Aspergillus nidulans MTCC344 using response surface methodology

SA Jabasingh, CV Nachiyar - Industrial Crops and Products, 2011 - Elsevier
Response surface methodology (RSM) was used to optimize the conditions for the
production of endo β-1, 4 glucanase, a component of cellulase by Aspergillus nidulans …

[HTML][HTML] Metabolômica de plantas: métodos e desafios

AC Pilon, DM Selegato, RP Fernandes, PCP Bueno… - Química …, 2020 - SciELO Brasil
Metabolomics has played a central role in various areas of plant sciences, offering new
perspectives for the advancement of agriculture, drug discovery, chemical ecology and …

Enhancement of cellulolytic enzyme production from intrageneric protoplast fusion of Aspergillus species and evaluating the hydrolysate scavenging activity

DA Goda, HM Shakam, ME Metwally… - Microbial Cell …, 2024 - Springer
Background Lignocellulosic biomass provides a great starting point for the production of
energy, chemicals, and fuels. The major component of lignocellulosic biomass is cellulose …