[HTML][HTML] The bidirectional relationship of depression and inflammation: double trouble

E Beurel, M Toups, CB Nemeroff - Neuron, 2020 - cell.com
Depression represents the number one cause of disability worldwide and is often fatal.
Inflammatory processes have been implicated in the pathophysiology of depression. It is …

Systematic review of gut microbiota and major depression

SG Cheung, AR Goldenthal, AC Uhlemann… - Frontiers in …, 2019 - frontiersin.org
Background: Recently discovered relationships between the gastrointestinal microbiome
and the brain have implications for psychiatric disorders, including major depressive …

The role of inflammation and the gut microbiome in depression and anxiety

JM Peirce, K Alviña - Journal of neuroscience research, 2019 - Wiley Online Library
The study of the gut microbiome has increasingly revealed an important role in modulating
brain function and mental health. In this review, we underscore specific pathways and …

Nerves in cancer

AH Zahalka, PS Frenette - Nature Reviews Cancer, 2020 - nature.com
The contribution of nerves to the pathogenesis of malignancies has emerged as an
important component of the tumour microenvironment. Recent studies have shown that …

[HTML][HTML] Gut microbiome diversity is associated with sleep physiology in humans

RP Smith, C Easson, SM Lyle, R Kapoor, CP Donnelly… - PloS one, 2019 - journals.plos.org
The human gut microbiome can influence health through the brain-gut-microbiome axis.
Growing evidence suggests that the gut microbiome can influence sleep quality. Previous …

Peripheral markers of depression

A Nobis, D Zalewski, N Waszkiewicz - Journal of clinical medicine, 2020 - mdpi.com
Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression

DR Goldsmith, MH Rapaport, BJ Miller - Molecular psychiatry, 2016 - nature.com
Schizophrenia, bipolar disorder and major depressive disorder (MDD) have all been
associated with aberrant blood cytokine levels; however, neither the pattern of cytokine …

[HTML][HTML] Origin and function of stress-induced IL-6 in murine models

H Qing, R Desrouleaux, K Israni-Winger, YS Mineur… - Cell, 2020 - cell.com
Acute psychological stress has long been known to decrease host fitness to inflammation in
a wide variety of diseases, but how this occurs is incompletely understood. Using mouse …

Depression and anxiety in patients with inflammatory bowel disease: a systematic review

R Neuendorf, A Harding, N Stello, D Hanes… - Journal of …, 2016 - Elsevier
Objective An increasing number of studies have been conducted to look at anxiety and
depression in IBD; however, there is no clear consensus on the prevalence of anxiety and …

So depression is an inflammatory disease, but where does the inflammation come from?

M Berk, LJ Williams, FN Jacka, A O'Neil, JA Pasco… - BMC medicine, 2013 - Springer
Background We now know that depression is associated with a chronic, low-grade
inflammatory response and activation of cell-mediated immunity, as well as activation of the …