Genetic predisposition and chromosome instability in neuroblastoma
Neuroblastoma (NB) is a pediatric tumor of embryonic origin. About 1–2% of all NBs are
familial cases, and genetic predisposition is suspected for the remaining cases. During the …
familial cases, and genetic predisposition is suspected for the remaining cases. During the …
Genetic susceptibility to neuroblastoma: current knowledge and future directions
Neuroblastoma, a malignancy of the develo** peripheral nervous system that affects
infants and young children, is a complex genetic disease. Over the past two decades …
infants and young children, is a complex genetic disease. Over the past two decades …
Association of potentially functional variants in the XPG gene with neuroblastoma risk in a Chinese population
XPG gene plays a critical role in the nucleotide excision repair pathway. However, the
association between XPG gene polymorphisms and neuroblastoma risk has not been …
association between XPG gene polymorphisms and neuroblastoma risk has not been …
Functional polymorphisms at ERCC1/XPF genes confer neuroblastoma risk in Chinese children
Variations in nucleotide excision repair pathway genes may predispose to initiation of
cancers. However, polymorphisms of ERCC1/XPF genes and neuroblastoma risk have not …
cancers. However, polymorphisms of ERCC1/XPF genes and neuroblastoma risk have not …
Racial and ethnic disparities in pediatric cancer incidence among children and young adults in the United States by single year of age
EL Marcotte, AM Domingues, JM Sample… - Cancer, 2021 - Wiley Online Library
Background Incidence rates of pediatric cancers in the United States are typically reported in
5‐year age groups, obscuring variation by single year of age. Additionally, racial and ethnic …
5‐year age groups, obscuring variation by single year of age. Additionally, racial and ethnic …
[HTML][HTML] Genetic variations of GWAS-identified genes and neuroblastoma susceptibility: a replication study in Southern Chinese children
Neuroblastoma is one of the most commonly diagnosed solid cancers for children, and
genetic factors may play a critical role in neuroblastoma development. Previous genome …
genetic factors may play a critical role in neuroblastoma development. Previous genome …
[HTML][HTML] Dualistic role of BARD1 in cancer
F Cimmino, D Formicola, M Capasso - Genes, 2017 - mdpi.com
BRCA1 Associated RING Domain 1 (BARD1) encodes a protein which interacts with the N-
terminal region of BRCA1 in vivo and in vitro. The full length (FL) BARD1 mRNA includes 11 …
terminal region of BRCA1 in vivo and in vitro. The full length (FL) BARD1 mRNA includes 11 …
BARD1 gene polymorphisms confer nephroblastoma susceptibility
W Fu, J Zhu, SW **ong, W Jia, Z Zhao, SB Zhu… - …, 2017 - thelancet.com
BRCA1-associated RING domain protein 1 (BARD1) is a tumor suppressor, which forms a
heterodimer with BRCA1. Three BARD1 gene polymorphisms (rs7585356 G> A, rs6435862 …
heterodimer with BRCA1. Three BARD1 gene polymorphisms (rs7585356 G> A, rs6435862 …
[HTML][HTML] The effects of genetic and epigenetic alterations of BARD1 on the development of non-breast and non-gynecological cancers
Br east Ca ncer 1 (BRCA1) gene is a well-characterized tumor suppressor gene, mutations
of which are primarily found in women with breast and ovarian cancers. B RCA1-a ssociated …
of which are primarily found in women with breast and ovarian cancers. B RCA1-a ssociated …
HOTAIR gene polymorphisms contribute to increased neuroblastoma susceptibility in Chinese children
BACKGROUND Neuroblastoma is the most frequently diagnosed extracranial solid tumor in
children. Previous studies have shown that single‐nucleotide polymorphisms in some genes …
children. Previous studies have shown that single‐nucleotide polymorphisms in some genes …