Abstract Cushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe
endocrine disease caused by a corticotroph pituitary tumor and associated with increased …

Objective: Our objective was to evaluate the published literature and reach a consensus on
the treatment of patients with ACTH-dependent Cushing's syndrome, because there is no …

Pituitary adenomas are common intracranial tumors that are mainly considered as benign.
Rarely, these tumors can exhibit an aggressive behavior, characterized by gross invasion of …

Background: The outcome of bilateral adrenalectomy (BADx) in patients with Cushing's
syndrome (CS) is not well characterized. Methods: A literature search was performed with …

Context: The diagnosis, differential diagnosis, and treatment of Cushing's syndrome are
challenging problems in clinical endocrinology. We focus on critical questions addressing …

Clinically nonfunctioning adenomas (CNFAs) range from being completely asymptomatic,
and therefore detected at autopsy or as incidental findings on head MRI or CT scans …

Background Cabergoline is a long-acting dopamine receptor agonist used to treat
prolactinomas. Identification of D2 receptors in corticotroph tumors led to clinical trials of …

Transsphenoidal surgery (TSS) is the initial treatment modality of first choice in Cushing's
disease (CD). With microscopic TSS and endoscopic TSS, two operative techniques with …

Objective Surgery for recurrent/residual pituitary adenomas is increasingly being performed
through endoscopic surgery. Whether this new technology has altered the indications and …

Pituitary adenomas are benign tumours comprising approximately 16% of all primary cranial
neoplasms. Functioning pituitary adenomas (prolactinomas, somatotroph, corticotroph …