[HTML][HTML] Antioxidant, antimicrobial and anticarcinogenic activities of bovine milk proteins and their hydrolysates-a review

M Bielecka, G Cichosz, H Czeczot - International Dairy Journal, 2022 - Elsevier
Milk proteins and the products of their hydrolysis are characterised by high levels of
biological activity. The health-promoting potential of bovine milk proteins, peptides and …

Lactoferrin's anti-cancer properties: Safety, selectivity, and wide range of action

A Cutone, L Rosa, G Ianiro, MS Lepanto… - Biomolecules, 2020 - mdpi.com
Despite recent advances in cancer therapy, current treatments, including radiotherapy,
chemotherapy, and immunotherapy, although beneficial, present attendant side effects and …

Lactoferrin in aseptic and septic inflammation

MS Lepanto, L Rosa, R Paesano, P Valenti, A Cutone - Molecules, 2019 - mdpi.com
Lactoferrin (Lf), a cationic glycoprotein able to chelate two ferric irons per molecule, is
synthesized by exocrine glands and neutrophils. Since the first anti-microbial function …

Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: an interventional study

MS Lepanto, L Rosa, A Cutone, MP Conte… - Frontiers in …, 2018 - frontiersin.org
The discovery of the ferroportin-hepcidin complex has led to a critical review on the
treatment of anemia and anemia of inflammation (AI). Ferroportin, the only known …

Antimicrobial peptides (AMPs) in the pathogenesis of Alzheimer's disease: implications for diagnosis and treatment

F Bruno, A Malvaso, S Canterini, AC Bruni - Antibiotics, 2022 - mdpi.com
Alzheimer's disease (AD) represents the most frequent type of dementia in elderly people.
There are two major forms of the disease: sporadic (SAD)—whose causes are not …

The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19

JK Mann, T Ndung'u - Future Virology, 2020 - Taylor & Francis
Coronavirus disease 2019 (COVID-19), caused by SARS coronavirus 2 (SARS-CoV-2), is
spreading rapidly with no established effective treatments. While most cases are mild, others …

Neuroprotective effects of lactoferrin in Alzheimer's and Parkinson's diseases: A narrative review

SJ Yong, A Veerakumarasivam, WL Lim… - ACS Chemical …, 2023 - ACS Publications
Recent advancements in lactoferrin research have uncovered that lactoferrin does function
not only as an antimicrobial protein but also as an immunomodulatory, anticancer, and …

Lactoferrin for prevention and treatment of anemia and inflammation in pregnant women: A comprehensive review

J Artym, M Zimecki, ML Kruzel - Biomedicines, 2021 - mdpi.com
Pregnancy is a physiological state that demands higher level of nutrients, including vitamins
and minerals, for the growth and maintenance of the fetus. Iron deficiency is a part of most …

Aerosolized Bovine Lactoferrin Counteracts Infection, Inflammation and Iron Dysbalance in A Cystic Fibrosis Mouse Model of Pseudomonas aeruginosa Chronic …

A Cutone, MS Lepanto, L Rosa, MJ Scotti… - International journal of …, 2019 - mdpi.com
Cystic fibrosis (CF) is a genetic disorder affecting several organs including airways. Bacterial
infection, inflammation and iron dysbalance play a major role in the chronicity and severity of …

Viral hepatitis and iron dysregulation: Molecular pathways and the role of lactoferrin

R Mancinelli, L Rosa, A Cutone, MS Lepanto… - Molecules, 2020 - mdpi.com
The liver is a frontline immune site specifically designed to check and detect potential
pathogens from the bloodstream to maintain a general state of immune …