Gut microbiota and cardiovascular disease

M Witkowski, TL Weeks, SL Hazen - Circulation research, 2020 - Am Heart Assoc
Fecal microbial community changes are associated with numerous disease states, including
cardiovascular disease (CVD). However, such data are merely associative. A causal …

Heart failure in type 2 diabetes mellitus: impact of glucose-lowering agents, heart failure therapies, and novel therapeutic strategies

HC Kenny, ED Abel - Circulation research, 2019 - Am Heart Assoc
Patients with diabetes mellitus have> 2× the risk for develo** heart failure (HF; HF with
reduced ejection fraction and HF with preserved ejection fraction). Cardiovascular …

Dietary metabolism, the gut microbiome, and heart failure

WHW Tang, DY Li, SL Hazen - Nature Reviews Cardiology, 2019 - nature.com
Advances in our understanding of how the gut microbiota contributes to human health and
diseases have expanded our insight into how microbial composition and function affect the …

Editor's Choice–2017 ESC guidelines on the diagnosis and treatment of peripheral arterial diseases, in collaboration with the European Society for Vascular Surgery …

V Aboyans, JB Ricco, MLEL Bartelink, M Björck… - European Journal of …, 2018 - ejves.com
Document Reviewers b, Petr Widimsky, Philippe Kolh, Stefan Agewall, Héctor Bueno,
Antonio Coca, Gert J. De Borst, Victoria Delgado, Florian Dick, Cetin Erol, Marc Ferrini …

Inflammation in Heart Failure: JACC State-of-the-Art Review

SP Murphy, R Kakkar, CP McCarthy… - Journal of the American …, 2020 - jacc.org
It has long been observed that heart failure (HF) is associated with measures of systemic
inflammation. In recent years, there have been significant advancements in our …

Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype

M Horckmans, L Ring, J Duchene… - European heart …, 2017 - academic.oup.com
Aims Acute myocardial infarction (MI) is the leading cause of mortality worldwide. Anti-
inflammatory strategies to reduce neutrophil-driven acute post-MI injury have been shown to …

Cytokines and cytokine receptors in advanced heart failure: an analysis of the cytokine database from the Vesnarinone trial (VEST)

A Deswal, NJ Petersen, AM Feldman, JB Young… - Circulation, 2001 - Am Heart Assoc
Background—Previous reports have shown that elevated circulating levels of cytokines
and/or cytokine receptors predict adverse outcomes in patients with heart failure. However …

[HTML][HTML] IL-10, IL-6, and TNF-α: central factors in the altered cytokine network of uremia—the good, the bad, and the ugly

P Stenvinkel, M Ketteler, RJ Johnson, B Lindholm… - Kidney international, 2005 - Elsevier
IL-10, IL-6, and TNF-α: Central factors in the altered cytokine network of uremia—The good,
the bad, and the ugly. It has been increasingly apparent that wasting and cardiovascular …

[HTML][HTML] TMAO: how gut microbiota contributes to heart failure

Y Zhang, Y Wang, B Ke, J Du - Translational Research, 2021 - Elsevier
An increasing amount of evidence reveals that the gut microbiota is involved in the
pathogenesis and progression of various cardiovascular diseases. In patients with heart …

[HTML][HTML] Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial

SS Schleithoff, A Zittermann, G Tenderich… - The American journal of …, 2006 - Elsevier
Background: Elevated circulating concentrations of proinflammatory cytokines may
contribute to the pathogenesis of congestive heart failure (CHF). In vitro studies suggest that …