Vitiligo: an update on pathophysiology and treatment options

R Speeckaert, N van Geel - American journal of clinical dermatology, 2017 - Springer
The pathophysiology of vitiligo is becoming increasingly clarified. In non-segmental vitiligo,
early factors include activation of innate immunity, inflammasome activation, oxidative stress …

Vitiligo: a review of the published work

R Yaghoobi, M Omidian… - The Journal of …, 2011 - Wiley Online Library
Vitiligo is a common depigmenting skin disorder, characterized by acquired, idiopathic,
progressive, circumscribed hypomelanosis of the skin and hair, with total absence of …

Vitiligo: A comprehensive overview: Part II: Treatment options and approach to treatment

LM Felsten, A Alikhan, V Petronic-Rosic - Journal of the American Academy …, 2011 - Elsevier
Vitiligo is a common skin disorder that results in depigmentation. With the appropriate
management, many patients can minimize disease progression, attain repigmentation, and …

Update on skin repigmentation therapies in vitiligo

R Falabella, MI Barona - Pigment Cell & Melanoma Research, 2009 - Wiley Online Library
Treatment for vitiligo is difficult and prolonged. Nevertheless, at present considerable
knowledge accumulated during several decades on the pathogenic mechanisms, revealed …

[HTML][HTML] Calcineurin inhibitors decrease DNA repair and apoptosis in human keratinocytes following ultraviolet B irradiation

DB Yarosh, AV Pena, SL Nay, MT Canning… - Journal of investigative …, 2005 - Elsevier
The use of calcineurin inhibitors in solid organ transplantation results in an increased risk of
skin cancer. We examined the effect of these drugs on DNA repair in normal human …

Physiopathology and genetics of vitiligo

T Passeron, JP Ortonne - Journal of autoimmunity, 2005 - Elsevier
Generalized vitiligo is an acquired disorder in which white patches of skin and overlying hair
result from autoimmune loss of melanocytes from involved areas. The autoimmune …

Narrowband ultraviolet B phototherapy and 308-nm excimer laser in the treatment of vitiligo: a review

E Nicolaidou, C Antoniou, A Stratigos… - Journal of the American …, 2009 - Elsevier
Vitiligo is a common and chronic disease with a great impact on patients' quality of life.
Phototherapy with narrowband ultraviolet B radiation and excimer laser are two treatment …

Narrow‐band UVB phototherapy combined with tacrolimus ointment in vitiligo: a review of 110 patients

D Fai, N Cassano, GA Vena - Journal of the European Academy …, 2007 - Wiley Online Library
Background Narrow‐band ultraviolet B (NB‐UVB) phototherapy and topical tacrolimus are
included among the most innovative approaches to vitiligo. Objective To evaluate the …

The efficacy of pimecrolimus 1% cream plus narrow-band ultraviolet B in the treatment of vitiligo: a double-blind, placebo-controlled clinical trial

I Esfandiarpour, A Ekhlasi, S Farajzadeh… - Journal of …, 2009 - Taylor & Francis
Background: Recently, narrow-band ultraviolet B (NB-UVB) and topical immunomodulators
have been successfully used in the treatment of vitiligo. Objective: To determine whether the …

A double‐blind, randomized, placebo‐controlled trial of topical tacrolimus 0· 1% vs. clobetasol propionate 0· 05% in childhood vitiligo

N Ho, E Pope, M Weinstein, S Greenberg… - British Journal of …, 2011 - academic.oup.com
Summary Background Both clobetasol propionate 0· 05%(CP 0· 05%) and tacrolimus 0·
1%(T 0· 1%) ointments have been shown to be efficacious and safe in treating vitiligo in the …