In this article we review the cellular and molecular mechanisms of gastric ulcer healing. A
gastric ulcer (GU) is a deep defect in the gastric wall penetrating through the entire mucosa …

Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) are some of the most
prescribed drugs worldwide and have now probably overtaken Helicobacter pylori as the …

The first scientific publication on 'general adaption syndrome', or as we know today 'biologic
stress' has been published in Nature in 1936 by the 29-year old Hans Selye. His results in …

The roles of proteinase-activated receptors (PARs) in platelet functions other than
aggregation are not well understood. Among these is the release of factors that regulate the …

Bleeding and delayed healing of ulcers are well recognized clinical problems associated
with the use of aspirin and other nonsteroidal antiinflammatory drugs, which have been …

We have shown that folate-induced kidney dysfunction and interstitial fibrosis predisposes
mice to sepsis mortality. Agents that increase survival in normal septic mice were ineffective …

In this study, the effects of fucoidan on aspirin-induced ulcers in rats were evaluated: both
biochemical and immunological parameters were taken into consideration. The status of …

Delayed gastric ulcer healing is a well recognized problem associated with the use of
cyclooxygenase (COX) inhibitors. In contrast, NO-releasing COX inhibitors do not interfere …

The significance of cytoprotection and adaptive cytoprotection and the peptides importance
remained to be not completely determined. BPC 157 is an anti-ulcer peptidergic agent …

Objective—To determine associations between age, sex, or medical treatment and
prevalence and severity of gastric ulceration in Standardbred racehorses in training. Design …