[HTML][HTML] Coumarin: A natural, privileged and versatile scaffold for bioactive compounds

A Stefanachi, F Leonetti, L Pisani, M Catto, A Carotti - Molecules, 2018 - mdpi.com
Many naturally occurring substances, traditionally used in popular medicines around the
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …

Development in the synthesis of bioactive thiazole-based heterocyclic hybrids utilizing phenacyl bromide

G Kumari, S Dhillon, P Rani, M Chahal, DK Aneja… - ACS …, 2024 - ACS Publications
Heterocyclic hybrid frameworks represent a burgeoning domain within the realms of drug
discovery and medicinal chemistry, attracting considerable attention in recent years …

Water-controlled selective preparation of α-mono or α, α′-dihalo ketones via catalytic cascade reaction of unactivated alkynes with 1, 3-dihalo-5, 5-dimethylhydantoin

C Wu, X **n, ZM Fu, LY **e, KJ Liu, Z Wang, W Li… - Green …, 2017 - pubs.rsc.org
The control of a reaction that can produce multiple products from the same starting material
is a highly attractive and challenging concept in organic synthesis. An efficient protocol for …

Study and applications of tetrasubstituted hypervalent selenium–halogen species in catalytic electrophilic halogenations

J Yang, YY Chan, W Feng, YLS Tse, YY Yeung - ACS Catalysis, 2023 - ACS Publications
Electrophilic halogenation reactions are highly useful in various areas. N-Haloamides are
commonly used as halogen sources because of high stability and commercial availability. In …

Recent Advances in the Electrochemical α‐C–H Bond Functionalization of Carbonyl Compounds

S Liang, K Xu, CC Zeng, HY Tian… - Advanced Synthesis & …, 2018 - Wiley Online Library
The α‐C–H functionalization of carbonyl compounds represents a cornerstone of organic
chemistry. Site‐selective α‐C− H bond functionalization of carbonyl compounds to afford …

Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid

S Song, X Li, X Sun, Y Yuan, N Jiao - Green Chemistry, 2015 - pubs.rsc.org
The oxidative bromination of olefins, alkynes, and ketones has been developed with HBr as
the brominating reagent and DMSO as the mild oxidant. The simple conditions, high …

BF3-Mediated Acetylation of Pyrazolo[1,5-a]pyrimidines and Other π-Excedent (N-Hetero)arenes

SL Aranzazu, A Tigreros, A Arias-Gómez… - The Journal of …, 2022 - ACS Publications
An operably simple microwave-assisted BF3-mediated acetylation reaction of pyrazolo [1, 5-
a] pyrimidines and a plausible mechanism based on density functional theory (DFT) …

Iron-catalyzed asymmetric haloazidation of α, β-unsaturated ketones: construction of organic azides with two vicinal stereocenters

P Zhou, L Lin, L Chen, X Zhong, X Liu… - Journal of the American …, 2017 - ACS Publications
Organic azides play important roles in synthetic chemistry, chemical biology, drug discovery,
and material science. Azido-functionalization of alkenes is one of the most efficient …

Coumarins synthesis and transformation via C–H bond activation—a Review

K Szwaczko - Inorganics, 2022 - mdpi.com
For several decades, coumarins have attracted considerable attention due to the fact of their
application in diverse fields such as medical science and biomedical research as well as …

Development of Customized [18F]Fluoride Elution Techniques for the Enhancement of Copper-Mediated Late-Stage Radiofluorination

AV Mossine, AF Brooks, N Ichiishi, KJ Makaravage… - Scientific Reports, 2017 - nature.com
In a relatively short period of time, transition metal-mediated radiofluorination reactions have
changed the PET radiochemistry landscape. These reactions have enabled the …