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[HTML][HTML] Coumarin: A natural, privileged and versatile scaffold for bioactive compounds
Many naturally occurring substances, traditionally used in popular medicines around the
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
world, contain the coumarin moiety. Coumarin represents a privileged scaffold for medicinal …
Development in the synthesis of bioactive thiazole-based heterocyclic hybrids utilizing phenacyl bromide
Heterocyclic hybrid frameworks represent a burgeoning domain within the realms of drug
discovery and medicinal chemistry, attracting considerable attention in recent years …
discovery and medicinal chemistry, attracting considerable attention in recent years …
Water-controlled selective preparation of α-mono or α, α′-dihalo ketones via catalytic cascade reaction of unactivated alkynes with 1, 3-dihalo-5, 5-dimethylhydantoin
C Wu, X **n, ZM Fu, LY **e, KJ Liu, Z Wang, W Li… - Green …, 2017 - pubs.rsc.org
The control of a reaction that can produce multiple products from the same starting material
is a highly attractive and challenging concept in organic synthesis. An efficient protocol for …
is a highly attractive and challenging concept in organic synthesis. An efficient protocol for …
Study and applications of tetrasubstituted hypervalent selenium–halogen species in catalytic electrophilic halogenations
J Yang, YY Chan, W Feng, YLS Tse, YY Yeung - ACS Catalysis, 2023 - ACS Publications
Electrophilic halogenation reactions are highly useful in various areas. N-Haloamides are
commonly used as halogen sources because of high stability and commercial availability. In …
commonly used as halogen sources because of high stability and commercial availability. In …
Recent Advances in the Electrochemical α‐C–H Bond Functionalization of Carbonyl Compounds
S Liang, K Xu, CC Zeng, HY Tian… - Advanced Synthesis & …, 2018 - Wiley Online Library
The α‐C–H functionalization of carbonyl compounds represents a cornerstone of organic
chemistry. Site‐selective α‐C− H bond functionalization of carbonyl compounds to afford …
chemistry. Site‐selective α‐C− H bond functionalization of carbonyl compounds to afford …
Efficient bromination of olefins, alkynes, and ketones with dimethyl sulfoxide and hydrobromic acid
The oxidative bromination of olefins, alkynes, and ketones has been developed with HBr as
the brominating reagent and DMSO as the mild oxidant. The simple conditions, high …
the brominating reagent and DMSO as the mild oxidant. The simple conditions, high …
BF3-Mediated Acetylation of Pyrazolo[1,5-a]pyrimidines and Other π-Excedent (N-Hetero)arenes
An operably simple microwave-assisted BF3-mediated acetylation reaction of pyrazolo [1, 5-
a] pyrimidines and a plausible mechanism based on density functional theory (DFT) …
a] pyrimidines and a plausible mechanism based on density functional theory (DFT) …
Iron-catalyzed asymmetric haloazidation of α, β-unsaturated ketones: construction of organic azides with two vicinal stereocenters
P Zhou, L Lin, L Chen, X Zhong, X Liu… - Journal of the American …, 2017 - ACS Publications
Organic azides play important roles in synthetic chemistry, chemical biology, drug discovery,
and material science. Azido-functionalization of alkenes is one of the most efficient …
and material science. Azido-functionalization of alkenes is one of the most efficient …
Coumarins synthesis and transformation via C–H bond activation—a Review
K Szwaczko - Inorganics, 2022 - mdpi.com
For several decades, coumarins have attracted considerable attention due to the fact of their
application in diverse fields such as medical science and biomedical research as well as …
application in diverse fields such as medical science and biomedical research as well as …
Development of Customized [18F]Fluoride Elution Techniques for the Enhancement of Copper-Mediated Late-Stage Radiofluorination
In a relatively short period of time, transition metal-mediated radiofluorination reactions have
changed the PET radiochemistry landscape. These reactions have enabled the …
changed the PET radiochemistry landscape. These reactions have enabled the …