Molecular and biochemical regulation of skeletal muscle metabolism
MD Zumbaugh, SE Johnson, TH Shi… - Journal of Animal …, 2022 - academic.oup.com
Skeletal muscle hypertrophy is a culmination of catabolic and anabolic processes that are
interwoven into major metabolic pathways, and as such modulation of skeletal muscle …
interwoven into major metabolic pathways, and as such modulation of skeletal muscle …
A glutathione activatable ion channel induces apoptosis in cancer cells by depleting intracellular glutathione levels
Cancer cells use elevated glutathione (GSH) levels as an inner line of defense to evade
apoptosis and develop drug resistance. In this study, we describe a novel 2, 4 …
apoptosis and develop drug resistance. In this study, we describe a novel 2, 4 …
The emerging roles of PHOSPHO1 and its regulated phospholipid homeostasis in metabolic disorders
Y Liu, Y Wu, M Jiang - Frontiers in Physiology, 2022 - frontiersin.org
Emerging evidence suggests that phosphoethanolamine/phosphocholine phosphatase 1
(PHOSPHO1), a specific phosphoethanolamine and phosphocholine phosphatase, is …
(PHOSPHO1), a specific phosphoethanolamine and phosphocholine phosphatase, is …
[HTML][HTML] Cadmium perturbed metabolomic signature in pancreatic beta cells correlates with disturbed metabolite profile in human urine
H Hong, J Xu, H He, X Wang, L Yang, P Deng… - Environment …, 2022 - Elsevier
Cd exposure has been demonstrated to induce a variety of metabolic disorders
accompanied with imbalance of glucose and lipid homeostasis. The metabolic toxicity of Cd …
accompanied with imbalance of glucose and lipid homeostasis. The metabolic toxicity of Cd …
Integrated metabolome and transcriptome analyses revealing the effects of thermal stress on lipid metabolism in juvenile turbot Scophthalmus maximus
T Zhao, A Ma, S Yang, Z Huang - Journal of Thermal Biology, 2021 - Elsevier
To gain insights into the influence of heat stress on lipid metabolism in juvenile turbot
(Scophthalmus maximus), we analyzed the correlations between data obtained by …
(Scophthalmus maximus), we analyzed the correlations between data obtained by …
Potential obesogenic effects of TBBPA and its alternatives TBBPS and TCBPA revealed by metabolic perturbations in human hepatoma cells
Y Yu, C Hao, M **ang, J Tian, H Kuang, Z Li - Science of The Total …, 2022 - Elsevier
To date, increasing numbers of studies have shown the obesogenic effects of
tetrabromobisphenol A (TBBPA). Tetrabromobisphenol S (TBBPS) and tetrachlorobisphenol …
tetrabromobisphenol A (TBBPA). Tetrabromobisphenol S (TBBPS) and tetrachlorobisphenol …
Metabolic profiles point out metabolic pathways pivotal in two glioblastoma (GBM) cell lines, U251 and U-87MG
Glioblastoma (GBM) is the most lethal central nervous system (CNS) tumor, mainly due to its
high heterogeneity, invasiveness, and proliferation rate. These tumors remain a therapeutic …
high heterogeneity, invasiveness, and proliferation rate. These tumors remain a therapeutic …
A comparison of high-throughput plasma NMR protocols for comparative untargeted metabolomics
Introduction When analyzing the human plasma metabolome with Nuclear Magnetic
Resonance (NMR) spectroscopy, the Carr–Purcell–Meiboom–Gill (CPMG) experiment is …
Resonance (NMR) spectroscopy, the Carr–Purcell–Meiboom–Gill (CPMG) experiment is …
Human Pancreatic Islets React to Glucolipotoxicity by Secreting Pyruvate and Citrate
J Perrier, M Nawrot, AM Madec, K Chikh, MA Chauvin… - Nutrients, 2023 - mdpi.com
Progressive decline in pancreatic beta-cell function is central to the pathogenesis of type 2
diabetes (T2D). Here, we explore the relationship between the beta cell and its nutritional …
diabetes (T2D). Here, we explore the relationship between the beta cell and its nutritional …
Esterase‐Activatable Synthetic M+/Cl− Channel Induces Apoptosis and Disrupts Autophagy in Cancer Cells
The formation of a supramolecular synthetic M+/Cl− channel in the membrane phospholipid
bilayer has been reported upon activation of a methyl pivalate‐linked N1, N3‐dialkyl‐2 …
bilayer has been reported upon activation of a methyl pivalate‐linked N1, N3‐dialkyl‐2 …