Abnormal enzymatic activities are directly related to the development of cancers. Identifying
the location and expression levels of these enzymes in live cancer cells have considerable …

Lipid droplets (LDs) have been known as a non-negligible cellular organelle for lipid storage
and metabolism. Fluorescent probes for imaging LDs would be paramount for depicting their …

A biomarker-based detection improves early diagnosis and subsequent treatment of
diseases. Chemo/biosensing and bioimaging play a crucial role in biomarker detection …

1, 8-Naphthalimide, as one of the classical dyes and fluorophores, has been widely used in
analytical chemistry, materials chemistry, and biochemistry fields because of its excellent …

Conspectus Enzymes are a class of important substances for life, and their abnormal levels
are associated with many diseases. Thus, great progress has been made in the past decade …

Fluorescent probes have long been valuable tools in the study of biological systems. With
the ever-expanding range of known enzymatic biomarkers for disease, it has never been …

The actions of many drugs involve enzyme inhibition. This is exemplified by the inhibitors of
monoamine oxidases (MAO) and the cholinsterases (ChE) that have been used for several …

Parkinson's disease (PD), as the second most common neurodegenerative disease, is
caused by complex pathological processes and currently remains very difficult to treat. PD …

In recent years, more and more chemists and biologists pay attention to the research of
fluorescent probes, and great progress has been made in the design and application. In this …

Fluorescence imaging of tyrosinase (a cancer biomarker) in living organisms is of great
importance for biological studies. However, selective detection of tyrosinase remains a great …