Despite declines in heart failure morbidity and mortality with current therapies,
rehospitalization rates remain distressingly high, substantially affecting individuals, society …

Objectives: The objectives of this review are to discuss the pathophysiology of the pro-
inflammatory response to the cardiopulmonary bypass circuit, the impact of ischemia …

Abstract Purpose of Review In heart failure, whether it is associated with reduced or
preserved ejection fraction, the immune system is activated and contributes to heart …

Despite numerous demonstrations that the immune system is activated in heart failure,
negatively affecting patients' outcomes, no definitive treatment strategy exists directed to …

Cardiovascular diseases, including hypertension and heart failure, are associated with
activation of the renin-angiotensin system (RAS) and increased circulating and tissue levels …

Heart failure (HF) is considered the endpoint of a variety of cardiac diseases, which are the
leading cause of death in adults and considered a growing pandemic worldwide …

The immune molecular mechanisms involved in ischaemic cardiomyopathy (ICM) have not
been fully elucidated. The current study aimed to elucidate the immune cell infiltration …

Heart disease remains the major cause of death in males and females, emphasizing the
need for novel strategies to improve patient treatment and survival. A therapeutic approach …

In the past decades, myocardial infarction periacute mortality markedly declined since
coronary reperfusion therapy has been adopted. Despite immediate benefits of coronary …

To further understand chronic heart disease, such as heart failure and cardiomyopathy, we
must fully define signaling pathways within the myocardium. Recent studies suggest that …