Highlights•Modern recording technologies are creating data at a scale and complexity that
demand rigorous data analytical approaches.•Neural data science is an essential bridge …

Advances in fluorescence microscopy enable monitoring larger brain areas in-vivo with finer
time resolution. The resulting data rates require reproducible analysis pipelines that are …

Fluorescent calcium indicators are a popular means for observing the spiking activity of
large neuronal populations, but extracting the activity of each neuron from raw fluorescence …

Dendritic calcium signaling is central to neural plasticity mechanisms that allow animals to
adapt to the environment. Intracellular calcium release (ICR) from the endoplasmic reticulum …

Long-lasting internal arousal states motivate and pattern ongoing behaviour, enabling the
temporary emergence of innate behavioural programs that serve the needs of an animal …

Neuronal ensembles are groups of neurons with correlated activity associated with sensory,
motor, and behavioral functions. To explore how ensembles encode information, we …

Neuronal ensembles, coactive groups of neurons found in spontaneous and evoked cortical
activity, are causally related to memories and perception, but it is still unknown how stable or …

In recent years, two-photon calcium imaging has become a standard tool to probe the
function of neural circuits and to study computations in neuronal populations. However, the …

Calcium imaging data promises to transform the field of neuroscience by making it possible
to record from large populations of neurons simultaneously. However, determining the exact …

Fluorescence microscopy allows for the high-throughput imaging of cellular activity across
brain areas in mammals. However, capturing rapid cellular dynamics across the curved …