Chemotherapy is one of the widely used anticancer treatments that involves the use of
powerful cytotoxic drugs to stop tumor growth by targeting rapidly dividing cells through …

Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …

Melatonin is a pleotropic molecule with numerous biological activities. Epidemiological and
experimental studies have documented that melatonin could inhibit different types of cancer …

Cisplatin is one of the most widely used chemotherapeutic drugs in the treatment of a wide
range of pediatric and adult malignances. However, it has various side effects which limit its …

As one of the problems and diseases for women before 40 years, premature ovarian failure
(POF) could be characterized by amenorrhea, low estrogen levels, infertility, high …

Ovarian damage and fertility impairment are major side effects of chemotherapy in pre-
menopausal cancer patients. Cisplatin is a widely used chemotherapeutic drug. The present …

BACKGROUND Chemotherapy-associated ovarian damage (CAOD) is one of the most
feared short-and long-term side effects of anticancer treatment in premenopausal women …

Sulfur and nitrogen mustards, bis (2-chloroethyl) sulfide and tertiary bis (2-chloroethyl)
amines, respectively, are vesicant warfare agents with alkylating activity. Moreover …

Incidence of premature ovarian failure (POF) is higher with the increase of the pace of life.
The etiology of POF is very complex, which is closely related to genes, immune diseases …

Melatonin is synthesized in the pineal gland at night. Since melatonin is produced in the
mitochondria of all other cells in a non-circadian manner, the amount synthesized by the …