Bioactive inorganic nanomaterials for cancer theranostics

Z Pei, H Lei, L Cheng - Chemical Society Reviews, 2023 - pubs.rsc.org
Bioactive materials are a special class of biomaterials that can react in vivo to induce a
biological response or regulate biological functions, thus achieving a better curative effect …

Recent progress in ferroptosis: inducers and inhibitors

Y Du, Z Guo - Cell death discovery, 2022 - nature.com
Ferroptosis is a new iron-dependent form of programmed cell death characterized by iron
accumulation and lipid peroxidation. In recent years, ferroptosis has garnered enormous …

“Electron transport chain interference” strategy of amplified mild-photothermal therapy and defect-engineered multi-enzymatic activities for synergistic tumor …

S Dong, Y Dong, Z Zhao, J Liu, S Liu… - Journal of the …, 2023 - ACS Publications
Arming activatable mild-photothermal therapy (PTT) with the property of relieving tumor
thermotolerance holds great promise for overcoming traditional mild PTT limitations such as …

Dual nanozyme-driven PtSn bimetallic nanoclusters for metal-enhanced tumor photothermal and catalytic therapy

Y Zhu, R Zhao, L Feng, C Wang, S Dong, MV Zyuzin… - ACS …, 2023 - ACS Publications
Specific generation of reactive oxygen species (ROS) within tumors in situ catalyzed by
nanozymes is a promising strategy for cancer therapeutics. However, it remains a significant …

Do** engineering to modulate lattice and electronic structure for enhanced piezocatalytic therapy and ferroptosis

B Tian, R Tian, S Liu, Y Wang, S Gai, Y **e… - Advanced …, 2023 - Wiley Online Library
Piezocatalytic therapy, which generates reactive oxygen species (ROS) under mechanical
force, has garnered extensive attention for its use in cancer therapy owing to its deep tissue …

Multi-enzyme co-expressed dual-atom nanozymes induce cascade immunogenic ferroptosis via activating interferon-γ and targeting arachidonic acid metabolism

Y Liu, R Niu, R Deng, S Song, Y Wang… - Journal of the American …, 2023 - ACS Publications
Immunotherapy is currently the most promising treatment strategy for long-term tumor
regression. However, current cancer immunotherapy shows low response rates due to …

A hollow amorphous bimetal organic framework for synergistic cuproptosis/ferroptosis/apoptosis anticancer therapy via disrupting intracellular redox homeostasis and …

W Xu, J Qian, G Hou, T Wang, J Wang… - Advanced Functional …, 2022 - Wiley Online Library
Cuproptosis is a very newly recognized regulated cell death modality that is distinct from
known death mechanisms and shows enormous prospect in cancer treatment. However, its …

H2O2 Self‐Producing Single‐Atom Nanozyme Hydrogels as Light‐Controlled Oxidative Stress Amplifier for Enhanced Synergistic Therapy by Transforming “Cold” …

D Zhu, H Chen, C Huang, G Li, X Wang… - Advanced Functional …, 2022 - Wiley Online Library
Single‐atom nanozyme (SAzyme) with peroxidase‐like activity can alter cellular redox
balance and shows promising potential for tumor therapy. However, the “cold” immune …

Copper doped carbon dots for addressing bacterial biofilm formation, wound infection, and tooth staining

M Liu, L Huang, X Xu, X Wei, X Yang, X Li, B Wang… - ACS …, 2022 - ACS Publications
Oral infectious diseases and tooth staining, the main challenges of dental healthcare, are
inextricably linked to microbial colonization and the formation of pathogenic biofilms …

MnOOH-catalyzed autoxidation of glutathione for reactive oxygen species production and nanocatalytic tumor innate immunotherapy

P Zhu, Y Pu, M Wang, W Wu, H Qin… - Journal of the American …, 2023 - ACS Publications
The antioxidant system, signed with reduced glutathione (GSH) overexpression, is the key
weapon for tumor to resist the attack by reactive oxygen species (ROS). Counteracting the …