Low dose spironolactone-mediated androgen-adiponectin modulation alleviates endocrine-metabolic disturbances in letrozole-induced PCOS
Polycystic ovarian syndrome (PCOS), is a multifactorial endocrine disorder in women of
reproductive age. It usually associates with metabolic disorders (MDs), which aggravates the …
reproductive age. It usually associates with metabolic disorders (MDs), which aggravates the …
Acetate restores hypothalamic-adipose kisspeptin status in a rat model of PCOS by suppression of NLRP3 immunoreactivity
Purpose Polycystic ovary syndrome (PCOS) is a complex reproductive event that is
delineated by endocrine/metabolic disorders. Alteration of kisspeptin status in the …
delineated by endocrine/metabolic disorders. Alteration of kisspeptin status in the …
Causal relationship between gut microbiota with subcutaneous and visceral adipose tissue: a bidirectional two-sample Mendelian Randomization study
F Cao, F Pan, X Gong, W Wang, Y Xu, P Cao… - Frontiers in …, 2023 - frontiersin.org
Background Numerous studies have revealed associations between gut microbiota and
adipose tissue. However, the specific functional bacterial taxa and their causal relationships …
adipose tissue. However, the specific functional bacterial taxa and their causal relationships …
Acetate rescues defective brain-adipose metabolic network in obese Wistar rats by modulation of peroxisome proliferator-activated receptor-γ
We investigated the hypothesis that acetate ameliorates brain-adipose metabolic
dysfunction (BAMED) in high fat diet (HFD)-induced obesity, possibly by modulation of …
dysfunction (BAMED) in high fat diet (HFD)-induced obesity, possibly by modulation of …
Chlorogenic acid restores ovarian functions in mice with letrozole-induced polycystic ovarian syndrome via modulation of adiponectin receptor
Around the world, polycystic ovary syndrome (PCOS) is a complex endocrine-metabolic
condition that typically affects 6–20% of females. Our study's major goal was to examine how …
condition that typically affects 6–20% of females. Our study's major goal was to examine how …
Protective role of melatonin against adipose-hepatic metabolic comorbidities in experimentally induced obese rat model
Background Adipose and hepatic metabolic dysfunctions are critical comorbidities that also
aggravate insulin resistance in obese individuals. Melatonin is a low-cost agent and …
aggravate insulin resistance in obese individuals. Melatonin is a low-cost agent and …
Combating hematopoietic and hepatocellular abnormalities resulting from administration of cisplatin: role of liver targeted glycyrrhetinic acid nanoliposomes loaded …
The effectiveness of cisplatin in cancer treatment renders its use vital to clinicians. However,
the accompanying side effects as cachexia, emesis and liver damage necessitate the use of …
the accompanying side effects as cachexia, emesis and liver damage necessitate the use of …
[HTML][HTML] Gallic acid reverses ovarian disturbances in mice with letrozole-induced PCOS via modulating Adipo R1 expression
Research question Women are increasingly suffering from polycystic ovary syndrome
(PCOS). Its pathophysiology is still unknown, though. The purpose of this study was to …
(PCOS). Its pathophysiology is still unknown, though. The purpose of this study was to …
Metformin treatment ameliorates endocrine-metabolic disturbances in letrozole-induced PCOS mice model by modulating adiponectin status
Background In reproductive aged women, polycystic ovarian syndrome (PCOS) is a complex
endocrine condition. It's generally linked to metabolic diseases (MDs), thereby increasing …
endocrine condition. It's generally linked to metabolic diseases (MDs), thereby increasing …
Acetate circumvents impaired metabolic switch in skeletal muscle of letrozole-induced PCOS rat model by suppression of PDK4/NLRP3
Objectives Endocrine disorders in women of childbearing age, including polycystic ovarian
syndrome (PCOS), have been linked to skeletal muscle insulin resistance with multiple post …
syndrome (PCOS), have been linked to skeletal muscle insulin resistance with multiple post …