Development and functional diversification of cortical interneurons

L Lim, D Mi, A Llorca, O Marín - Neuron, 2018 - cell.com
In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …

Development and arealization of the cerebral cortex

CR Cadwell, A Bhaduri, MA Mostajo-Radji, MG Keefe… - Neuron, 2019 - cell.com
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …

[HTML][HTML] Single-cell delineation of lineage and genetic identity in the mouse brain

RC Bandler, I Vitali, RN Delgado, MC Ho… - Nature, 2022 - nature.com
During neurogenesis, mitotic progenitor cells lining the ventricles of the embryonic mouse
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …

[HTML][HTML] Molecular diversity and specializations among the cells of the adult mouse brain

A Saunders, EZ Macosko, A Wysoker, M Goldman… - Cell, 2018 - cell.com
The mammalian brain is composed of diverse, specialized cell populations. To
systematically ascertain and learn from these cellular specializations, we used Drop-seq to …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Genetic and activity-dependent mechanisms underlying interneuron diversity

B Wamsley, G Fishell - Nature Reviews Neuroscience, 2017 - nature.com
The proper construction of neural circuits requires the generation of diverse cell types, their
distribution to defined regions, and their specific and appropriate wiring. A major objective in …

Interneuron types as attractors and controllers

G Fishell, A Kepecs - Annual review of neuroscience, 2020 - annualreviews.org
Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …

Genetic and epigenetic coordination of cortical interneuron development

KC Allaway, MI Gabitto, O Wapinski, G Saldi, CY Wang… - Nature, 2021 - nature.com
One of the hallmarks of the cerebral cortex is the extreme diversity of interneurons,–. The two
largest subtypes of cortical interneurons, parvalbumin-and somatostatin-positive cells, are …

[HTML][HTML] High-throughput map** of single-neuron projections by sequencing of barcoded RNA

JM Kebschull, PG Da Silva, AP Reid, ID Peikon… - Neuron, 2016 - cell.com
Neurons transmit information to distant brain regions via long-range axonal projections. In
the mouse, area-to-area connections have only been systematically mapped using bulk …

Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain

C Chung, X Yang, RF Hevner, K Kennedy, KI Vong… - Nature, 2024 - nature.com
Debate remains around the anatomical origins of specific brain cell subtypes and lineage
relationships within the human forebrain,,,,,–. Thus, direct observation in the mature human …