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Development and functional diversification of cortical interneurons
In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …
collection of cell types that are characterized by their unique spatial and temporal …
Development and arealization of the cerebral cortex
Adult cortical areas consist of specialized cell types and circuits that support unique higher-
order cognitive functions. How this regional diversity develops from an initially uniform …
order cognitive functions. How this regional diversity develops from an initially uniform …
[HTML][HTML] Single-cell delineation of lineage and genetic identity in the mouse brain
During neurogenesis, mitotic progenitor cells lining the ventricles of the embryonic mouse
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …
brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic …
[HTML][HTML] Molecular diversity and specializations among the cells of the adult mouse brain
A Saunders, EZ Macosko, A Wysoker, M Goldman… - Cell, 2018 - cell.com
The mammalian brain is composed of diverse, specialized cell populations. To
systematically ascertain and learn from these cellular specializations, we used Drop-seq to …
systematically ascertain and learn from these cellular specializations, we used Drop-seq to …
Hippocampal GABAergic inhibitory interneurons
KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …
of the total neuronal population; however, their remarkable anatomical and physiological …
Genetic and activity-dependent mechanisms underlying interneuron diversity
The proper construction of neural circuits requires the generation of diverse cell types, their
distribution to defined regions, and their specific and appropriate wiring. A major objective in …
distribution to defined regions, and their specific and appropriate wiring. A major objective in …
Interneuron types as attractors and controllers
Cortical interneurons display striking differences in shape, physiology, and other attributes,
challenging us to appropriately classify them. We previously suggested that interneuron …
challenging us to appropriately classify them. We previously suggested that interneuron …
Genetic and epigenetic coordination of cortical interneuron development
One of the hallmarks of the cerebral cortex is the extreme diversity of interneurons,–. The two
largest subtypes of cortical interneurons, parvalbumin-and somatostatin-positive cells, are …
largest subtypes of cortical interneurons, parvalbumin-and somatostatin-positive cells, are …
[HTML][HTML] High-throughput map** of single-neuron projections by sequencing of barcoded RNA
Neurons transmit information to distant brain regions via long-range axonal projections. In
the mouse, area-to-area connections have only been systematically mapped using bulk …
the mouse, area-to-area connections have only been systematically mapped using bulk …
Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain
Debate remains around the anatomical origins of specific brain cell subtypes and lineage
relationships within the human forebrain,,,,,–. Thus, direct observation in the mature human …
relationships within the human forebrain,,,,,–. Thus, direct observation in the mature human …