The Lachnospiraceae is a family of anaerobic bacteria in the class Clostridia with potential
to advance the bio-economy and intestinal therapeutics. Some species of Lachnospiraceae …

Techniques by which to genetically manipulate members of the microbiota enable both the
evaluation of host-microbe interactions and an avenue by which to monitor and modulate …

Site-specific recombinases such as the Cre-LoxP system are routinely used for genome
engineering in both prokaryotes and eukaryotes. Importantly, recombinases complement the …

The sustainable production of solvents from above ground carbon is highly desired. Several
clostridia naturally produce solvents and use a variety of renewable and waste-derived …

DNA has been pursued as a novel biomaterial for digital data storage. While large‐scale
data storage and random access have been achieved in DNA oligonucleotide pools …

Control of gene expression is fundamental to cell engineering. Here we demonstrate a set of
approaches to tune gene expression in Clostridia using the model Clostridium …

The removal of unwanted genetic material is a key aspect in many synthetic biology efforts
and often requires preliminary knowledge of which genomic regions are dispensable …

The Cre-Lox system is a highly versatile and powerful DNA recombinase mechanism,
mainly used in genetic engineering to insert or remove desired DNA sequences. It is widely …

Erwinia mallotivora is the causal agent of papaya dieback disease, a devastating diseases
affecting papaya production in Malaysia. Preliminary omics studies had successfully …

Abstract The Cre-Lox system is a highly versatile and powerful DNA recombinase
mechanism, mainly used in genetic engineering to insert or remove desired DNA …