Dietary linoleic acid and human health: Focus on cardiovascular and cardiometabolic effects

F Marangoni, C Agostoni, C Borghi, AL Catapano… - Atherosclerosis, 2020 - Elsevier
This narrative review aims to discuss the more relevant evidence on the role of linoleic acid
(LA), a n-6 essential fatty acid that constitutes the predominant proportion of dietary …

Metabolic regulation of the immune system in health and diseases: mechanisms and interventions

T Hu, CH Liu, M Lei, Q Zeng, L Li, H Tang… - Signal Transduction and …, 2024 - nature.com
Metabolism, including glycolysis, oxidative phosphorylation, fatty acid oxidation, and other
metabolic pathways, impacts the phenotypes and functions of immune cells. The metabolic …

[HTML][HTML] Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity

CBN Lauson, S Tiberti, PA Corsetto, F Conte, P Tyagi… - Cell Metabolism, 2023 - cell.com
The metabolic state represents a major hurdle for an effective adoptive T cell therapy (ACT).
Indeed, specific lipids can harm CD8+ T cell (CTL) mitochondrial integrity, leading to …

Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies

K Hildreth, SD Kodani, BD Hammock, L Zhao - The Journal of nutritional …, 2020 - Elsevier
Linoleic acid (LA) is the most abundant polyunsaturated fatty acid found in the Western diet.
Cytochrome P450-derived LA metabolites 9, 10-epoxyoctadecenoic acid (9, 10-EpOME), 12 …

[HTML][HTML] Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia

OY Kim, J Song - Life Sciences, 2024 - Elsevier
Metabolic syndrome (MetS), which is characterized by insulin resistance, high blood
glucose, obesity, and dyslipidemia, is known to increase the risk of dementia accompanied …

[BUCH][B] Normy żywienia dla populacji Polski i ich zastosowanie

M Jarosz, E Rychlik, K Stoś, J Charzewska - 2020 - ncez.pzh.gov.pl
Normy żywienia dla populacji Polski przez wiele lat były opracowywane przez ekspertów
Instytutu Żywności i Żywienia (IŻŻ). Również prace nad tym wydaniem początkowo były …

Fatty acids and cardiovascular risk. Evidence, lack of evidence, and diligence

F Visioli, A Poli - Nutrients, 2020 - mdpi.com
One of the most controversial areas of nutrition research relates to fats, particularly essential
fatty acids, in the context of cardiovascular disease risk. A critical feature of dietary fatty acids …

Beneficial effects of linoleic acid on cardiometabolic health: an update

KH Jackson, WS Harris, MA Belury… - Lipids in Health and …, 2024 - Springer
Linoleic acid (LA), as a part of the wider debate about saturated, omega-6 and omega-3 fatty
acids (FAs) and health, continues to be at the center of controversy in the world of fatty acid …

[HTML][HTML] Linoleic acid improves PIEZO2 dysfunction in a mouse model of Angelman Syndrome

LO Romero, R Caires, A Kaitlyn Victor… - Nature …, 2023 - nature.com
Angelman syndrome (AS) is a neurogenetic disorder characterized by intellectual disability
and atypical behaviors. AS results from loss of expression of the E3 ubiquitin-protein ligase …

[HTML][HTML] Functional lipids and cardiovascular disease reduction: a concise review

DO Omachi, ANA Aryee, JO Onuh - Nutrients, 2024 - mdpi.com
Functional lipids are dietary substances that may have an impact on human health by
lowering the risk of chronic illnesses and enhancing the quality of life. Numerous functional …