Cyber-medical systems are revolutionizing medicine. Mathematical therapy optimization is
one of the main pioneering results of cyber-medical system approach. Mathematical therapy …

Simple Summary As computer performance continues to grow at more affordable costs,
mathematical modelling and in silico experimentation begin to play a larger role in …

Optimized therapies for the individual patient provide a more cost-effective, more secure
method of chemotherapy. Therapy optimization demands a reliable mathematical model of …

Therapy optimization and personalization in cancer treatment requires reliable mathematical
models. A key issue in personalization is the identification of the model parameters. We …

One of the promising directions in future medicine is the optimization of therapies based on
mathematical and engi-neering methods, with which the treatment can be personalized. In …

In this article, we aim to apply mathematical modelling by means of eight first-order ordinary
differential equations to investigate the response of prostate cancer and the immune system …

Fluorescent live cell imaging is a widely used method in studying in vitro cell cultures, thus
the behavior of in vitro tumor spheroids can be examined cheaply and simply over several …

Angiogenesis, the formation of new blood vessels, is critical in both normal and pathological
contexts, especially cancer. This process involves complex interactions among endothelial …

In this paper, we explore the application of Chimeric Antigen Receptor (CAR) T cell therapy
for the treatment of Acute Lymphocytic Leukaemia (ALL) by means of in silico …

This paper deals with a recently reported mathematical model formulated by five first-order
ordinary differential equations that describe glucoregulatory dynamics. As main …