Fly Me to the Micron: Microtechnologies for Drosophila Research

UM Sonmez, N Frey, PR LeDuc… - Annual Review of …, 2024 - annualreviews.org
Multicellular model organisms, such as Drosophila melanogaster (fruit fly), are frequently
used in a myriad of biological research studies due to their biological significance and …

Robotic cell injection system with position and force control: Toward automatic batch biomanipulation

HB Huang, D Sun, JK Mills… - IEEE transactions on …, 2009 - ieeexplore.ieee.org
Biological cell injection is laborious work that requires lengthy training and suffers from a low
success rate. In this paper, a robotic cell-injection system for automatic injection of batch …

Invertebrate models for biomedical research, testing, and education

SE Wilson-Sanders - ILAR journal, 2011 - academic.oup.com
Invertebrate animals have been used as medicinals for 4,000 years and have served as
models for research and teaching since the late 1800s. Interest in invertebrate models has …

Mechanical characterization of human red blood cells under different osmotic conditions by robotic manipulation with optical tweezers

Y Tan, D Sun, J Wang, W Huang - IEEE Transactions on …, 2010 - ieeexplore.ieee.org
The physiological functions of human red blood cells (RBCs) play a crucial role to human
health and are greatly influenced by their mechanical properties. Any alteration of the cell …

A survey of force-assisted robotic cell microinjection technologies

Y Wei, Q Xu - IEEE Transactions on Automation Science and …, 2018 - ieeexplore.ieee.org
Cell injection plays an important role in genetics, transgenics, molecular biology, drug
discovery, reproductive study, and other biomedical fields. Compared with manual cell …

Integrated sensing for ionic polymer–metal composite actuators using PVDF thinfilms

Z Chen, Y Shen, N **, X Tan - Smart Materials and Structures, 2007 - iopscience.iop.org
Compact sensing methods are desirable for ionic polymer–metal composite (IPMC)
actuators in microrobotic and biomedical applications. In this paper a novel sensing scheme …

Mechanical modeling of biological cells in microinjection

Y Tan, D Sun, W Huang… - IEEE Transactions on …, 2008 - ieeexplore.ieee.org
Microinjection is an effective technique to introduce foreign materials into a biological cell.
Although some semi-automatic and fully-automatic microinjection systems have been …

Integrated IPMC/PVDF sensory actuator and its validation in feedback control

Z Chen, KY Kwon, X Tan - Sensors and Actuators A: Physical, 2008 - Elsevier
Position and/or force feedback is critical in ensuring precise and safe operation of ionic
polymer–metal composite (IPMC) actuators in bio/micromanipulation. In this paper the …

A rate-dependent cell microinjection model based on membrane theory

S Kang, Z Song, X Yang, Y Li… - Journal of …, 2023 - asmedigitalcollection.asme.org
As an effective method to deliver external materials into biological cells, microinjection has
been widely applied in the biomedical field. However, the knowledge of cell mechanical …

A novel multi-axis force sensor for microrobotics applications

RJ Wood, KJ Cho, K Hoffman - Smart materials and structures, 2009 - iopscience.iop.org
High performance force sensors often encounter the conflicting requirements of fine
sensitivity and wide bandwidth. While there is an intrinsic tradeoff between these two metrics …