Green Synthesis of Molecules for the Treatment of Neglected Diseases
JM Anghinoni, MC Dilelio… - Current Topics in …, 2023 - benthamdirect.com
Neglected tropical diseases (NTDs) affect mainly poor and marginalized populations of
tropical and subtropical areas in 150 countries. Many of the chemical processes involved in …
tropical and subtropical areas in 150 countries. Many of the chemical processes involved in …
Screening of the antileishmanial and antiplasmodial potential of synthetic 2-arylquinoline analogs
In this study, six analogs of 2-arylquinoline were synthesized and evaluated for their in vitro
and in vivo antiplasmodial and leishmanicidal activity. At a later stage, hemolytic activity and …
and in vivo antiplasmodial and leishmanicidal activity. At a later stage, hemolytic activity and …
Multi-targeting derivatives of (±)-aminoglutethimide: Synthesis, anti-leishmanial, cytotoxicity against cancerous cells and molecular docking studies
During the current study, we have synthesized 15 (8a-o) new substituted benzylamine
analogs of (±)-aminoglutethimide (6) by using standard methods being employed in organic …
analogs of (±)-aminoglutethimide (6) by using standard methods being employed in organic …
Synthesis of halogenated benzimidazolyl-C-nucleosides and their activity against Leishmania major and Leishmania tropica
Here we report the short synthesis of “reversed” halogenated C-nucleoside (benzimidazole)
analogs. Initially, 1, 2; 3, 4 vicinal diols of D-galactose were acetylated with two different …
analogs. Initially, 1, 2; 3, 4 vicinal diols of D-galactose were acetylated with two different …
Anti-leishmanial physalins—Phytochemical investigation, in vitro evaluation against clinical and MIL-resistant L. tropica strains and in silico studies
Cutaneous leishmaniasis (CL) is a major health problem in over 98 countries of the world,
including Pakistan. The current treatments are associated with a number of adverse effects …
including Pakistan. The current treatments are associated with a number of adverse effects …
Rational computational approaches to predict novel drug candidates against leishmaniasis
The combination of in silico and in vitro approaches has proven to be useful for the pre-
clinical assessment of potential drugs and novel uses for old drugs. This is frequently …
clinical assessment of potential drugs and novel uses for old drugs. This is frequently …
Leishmaniasis y su Resistencia a Fármacos: Un Enfoque Bibliométrico
CAB Gaibor - Estudios y Perspectivas Revista Científica …, 2024 - estudiosyperspectivas.org
El desarrollo de resistencia a los fármacos leishmanicidas representa un reto significativo
en el control de la leishmaniasis, debido a la disminución de la eficacia de los tratamientos …
en el control de la leishmaniasis, debido a la disminución de la eficacia de los tratamientos …