Melatonin signaling and cell protection function

F Luchetti, B Canonico, M Betti… - The FASEB …, 2010 - Wiley Online Library
Besides its well‐known regulatory role on circadian rhythm, the pineal gland hormone
melatonin has other biological functions and a distinct metabolism in various cell types and …

A critical review of polychlorinated biphenyls metabolism, metabolites, and their correlation with oxidative stress

J Liu, Y Tan, E Song, Y Song - Chemical research in toxicology, 2020 - ACS Publications
Polychlorinated biphenyls (PCBs) are notorious persistent organic pollutants that were
banned in the last century. However, PCBs still remain ubiquitous in the ecosystem due to …

[HTML][HTML] Quercetin attenuates brain oxidative alterations induced by iron oxide nanoparticles in rats

MF Dora, NM Taha, MA Lebda, AE Hashem… - International Journal of …, 2021 - mdpi.com
Iron oxide nanoparticle (IONP) therapy has diverse health benefits but high doses or
prolonged therapy might induce oxidative cellular injuries especially in the brain. Therefore …

Chronic neurodegeneration by aflatoxin B1 depends on alterations of brain enzyme activity and immunoexpression of astrocyte in male rats

A Alsayyah, R ElMazoudy, M Al-Namshan… - Ecotoxicology and …, 2019 - Elsevier
Aflatoxin B1 poses the greatest risk among the mycotoxins to target-organisms particularly
human, however, no studies addressed the neurotoxicity of chronic exposure of aflatoxin …

The role of mycotoxins in neurodegenerative diseases: current state of the art and future perspectives of research

VTT Nguyen, S König, S Eggert, K Endres… - Biological …, 2022 - degruyter.com
Mycotoxins are fungal metabolites that can cause various diseases in humans and animals.
The adverse health effects of mycotoxins such as liver failure, immune deficiency, and …

The relation of high fat diet, metabolic disturbances and brain oxidative dysfunction: modulation by hydroxy citric acid

KA Amin, HH Kamel, MA Abd Eltawab - Lipids in health and disease, 2011 - Springer
Aims This study aimed to examine the effect of high fat diet (HFD) to modulate brain
dysfunction, and understand the linkages between obesity, metabolic disturbances and the …

Effect of quercetin on haematobiochemical and histological changes in the liver of polychlorined biphenyls‐induced adult male Wistar rats

K Selvakumar, S Bavithra, S Suganya… - Journal of …, 2013 - Wiley Online Library
Polychlorinated biphenyls exposure damages the rat liver cells. Hematological parameters
such as hemoglobin, packed cell volume, red‐blood cells, white‐blood cells, neutrophils …

NMR-based metabolomics in pediatric drug resistant epilepsy–preliminary results

Ł Boguszewicz, E Jamroz, M Ciszek, E Emich-Widera… - Scientific reports, 2019 - nature.com
Epilepsy in children is the most frequent, heterogeneous and difficult to classify chronic
neurologic condition with the etiology found in 35–40% of patients. Our aim is to detect the …

Hyptis verticillata attenuates dyslipidaemia, oxidative stress and hepato-renal damage in streptozotocin-induced diabetic rats

I Ogar, GE Egbung, VU Nna, IJ Atangwho, EH Itam - Life sciences, 2019 - Elsevier
Aims Chronic hyperglycaemia in diabetes mellitus (DM) increases the production of free
radicals which results in oxidative stress and related disorders such as cardiovascular …

Pollutant accumulation patterns in nestlings of an avian top predator: biochemical and metabolic effects

ME Ortiz-Santaliestra, J Resano-Mayor… - Science of the Total …, 2015 - Elsevier
The exposure to persistent pollutants such as organochlorine compounds (OCs) or metals
has been associated with declines in top predator populations, which can accumulate high …