RNA modification in cardiovascular disease: implications for therapeutic interventions
C Wang, X Hou, Q Guan, H Zhou, L Zhou… - … and Targeted Therapy, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death in the world, with a high
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …
[HTML][HTML] Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer's disease
Microglia are critical in brain development and Alzheimer's disease (AD) etiology. Down
syndrome (DS) is the most common genetic developmental disorder and risk factor for AD …
syndrome (DS) is the most common genetic developmental disorder and risk factor for AD …
The tristetraprolin family of RNA-binding proteins in cancer: progress and future prospects
Y Saini, J Chen, S Patial - Cancers, 2020 - mdpi.com
Post-transcriptional regulation of gene expression plays a key role in cellular proliferation,
differentiation, migration, and apoptosis. Increasing evidence suggests dysregulated post …
differentiation, migration, and apoptosis. Increasing evidence suggests dysregulated post …
The ZFP36 family of RNA binding proteins regulates homeostatic and autoreactive T cell responses
ME Cook, TR Bradstreet, AM Webber, J Kim… - Science …, 2022 - science.org
RNA binding proteins are important regulators of T cell activation, proliferation, and cytokine
production. The zinc finger protein 36 (ZFP36) family genes (Zfp36, Zfp36l1, and Zfp36l2) …
production. The zinc finger protein 36 (ZFP36) family genes (Zfp36, Zfp36l1, and Zfp36l2) …
M6AREG: m6A-centered regulation of disease development and drug response
As the most prevalent internal modification in eukaryotic RNAs, N 6-methyladenosine (m6A)
has been discovered to play an essential role in cellular proliferation, metabolic …
has been discovered to play an essential role in cellular proliferation, metabolic …
HNRNPC downregulation inhibits IL‐6/STAT3‐mediated HCC metastasis by decreasing HIF1A expression
D Liu, X Luo, M ** muscle invasiveness and patient outcome …