Increasing evidence indicates that inflammation can cause thrombosis by a von Willebrand
factor (VWF)-mediated mechanism that includes endothelial activation, secretion of VWF …

Beyond its role in hemostasis, von Willebrand factor (VWF) is an emerging mediator of
vascular inflammation. Recent studies highlight the involvement of VWF and its regulator …

The vascular endothelium is involved in the production of many important substances which
are involved in cardiovascular pathophysiology. One such substance which is synthesised …

Factor VIII: C levels show a familial clustering, which remains after adjustment for the
influence of vWF and blood group. 46 Analysis of familial aggregation of factor VIII levels …

Gram-negative septic shock is mediated in part by endotoxin (lipopolysaccharide; LPS), and
animal models have shown that blockade of even single adhesion molecules considerably …

Increased levels of von Willebrand factor (vWf) and C-reactive protein (CRP) predict
cardiovascular mortality in selected populations. It is uncertain whether vWf and CRP predict …

Relations of factor VIII activity, FVIIIC, and von Willebrand factor antigen (vWFAg), with
ischaemic heart disease (IHD) were examined in 1393 men aged between 40 and 64 years …

Aims To determine whether circulating von Willebrand factor concentrations are
prospectively related to risk of coronary heart disease in the general population. Methods …

304 lets, GPIIb/IIIa (integrin αIIbβ3) that is abundantly present on platelets changes its
conformation to allow it to bind its ligands, VWF and fibrinogen20, 21). A part (~ 30%) of …

nously or administered subcutaneously or intranasally to humans, this compound induces a
rapid, 2-to 3-fold increase of plasma vWF that lasts 4 to 6 hours. 17 Desmopressin itself is …