Resistance to antimicrobial drugs is currently a serious threat to human health.
Consequently, we are facing an urgent need for new antimicrobial drugs acting with original …

P. nigrum L. extracts and the piperine alkaloid have important antimicrobial, anti-
inflammatory, and antioxidant properties. Therefore, in this study, we evaluated the …

This study aimed to evaluate the effect of a methoxylated fraction from Vellozia dasypus
Seub on myeloperoxidase (MPO)-chlorinating activity and subsequent in silico assays for …

Lectins that bind to HIV envelope glycoprotein can inhibit virus-cell fusion and be used for
rational drug design. This paper presents the results of an in silico approach to improve …

The cyclooxygenase-2 receptor is a therapeutic target for planning potential drugs with anti-
inflammatory activity. The selective cyclooxygenase-2 (COX-2) inhibitor rofecoxib was …

Non-steroidal anti-inflammatory drugs are inhibitors of cyclooxygenase-2 (COX-2) that were
developed in order to avoid the side effects of non-selective inhibitors of COX-1. Thus, the …

Glioblastoma is an aggressive primary tumor of the central nervous system (CNS). Is the
most aggressive among infiltrative gliomas arising from the CNS. This tumor has low patient …

Serratiopeptidase is the multifunctionality metalloendopeptidase extensively employed in
biopharmaceutical and industrial biotechnology. Despite its poor pH tolerance …

Polygala boliviensis is found in the Brazilian semiarid region. This specie is little chemically
and biologically studied. Polygala spp. have different metabolites, especially coumarins …

The biological activities of Eleutherine plicata Herb. have been linked to isoeleutherin and
eleutherin naphthoquinones. However, there are few reports in the literature regarding the …