Helix-loop-helix (HLH) proteins play a profound role in the process of development and
cellular differentiation. Among the HLH proteins expressed in differentiating erythroid cells …

Panax notoginseng (Burk.) FH Chen is a medicinal herb used to treat blood disorders since
ancient times, of which the steamed form exhibits the anti-anemia effect and acts with a …

Abstract Ablation of miR‐144/451 disrupts homeostasis of erythropoiesis. Myc, a
protooncogenic protein, is essential for erythroblast proliferation but commits rapid …

Diamond–Blackfan anemia (DBA), a rare congenital disorder characterized by a decrease in
erythroid precursor cells, has recently become a model for genetic diseases linked to …

Acute myeloid leukemias (AML) are characterized by recurrent genomic alterations, often in
transcriptional regulators, which form the basis on which current prognostication and …

Diamond-Blackfan anemia (DBA) is a rare congenital syndrome that presents with ane-mia
and selective deficiency of erythroid precursors, while other blood lineages are usu-ally …

Einer der essentiellen Masterregulatoren der Hämatopoese ist das T-cell acute lymphocytic
leukemia protein 1 (TAL1). Neben seiner Rolle während der Selbsterneuerung langzeit …