A review of the efficacy and safety of oral antidiabetic drugs

SA Stein, EM Lamos, SN Davis - Expert opinion on drug safety, 2013 - Taylor & Francis
Introduction: Additional oral antidiabetic agents to metformin, sulfonylureas (SU) and
thiazolidinediones (TZD) are approved for the treatment of type 2 diabetes. Areas covered …

Pharmacologic treatment of type 2 diabetes: oral medications

L Tran, A Zielinski, AH Roach… - Annals of …, 2015 - journals.sagepub.com
Objective: To review the oral and injectable pharmacologic treatment options for type 2
diabetes. Data Sources: A literature search was conducted using PubMed electronic …

[PDF][PDF] Late stage complications of diabetes and insulin resistance

D Soumya, B Srilatha - J Diabetes Metab, 2011 - researchgate.net
Diabetes mellitus is considered one of the main threats to human health in the 21st century.
Diabetes is a metabolic disorder or a chronic condition where the sugar levels in blood are …

Brain dopamine–clock interactions regulate cardiometabolic physiology: mechanisms of the observed cardioprotective effects of circadian-timed bromocriptine-QR …

AH Cincotta - International Journal of Molecular Sciences, 2023 - mdpi.com
Despite enormous global efforts within clinical research and medical practice to reduce
cardiovascular disease (s)(CVD), it still remains the leading cause of death worldwide. While …

A review of dopamine agonist therapy in type 2 diabetes and effects on cardio-metabolic parameters

EM Lamos, DL Levitt, KM Munir - Primary care diabetes, 2016 - Elsevier
Dopamine action appears to play a role in changes that are seen in obesity, metabolic
syndrome and type 2 diabetes mellitus. Bromocriptine-QR (Quick Release), a dopamine …

Pharmacological treatment of diabetes in older people

WM Valencia, H Florez - Diabetes, Obesity and Metabolism, 2014 - Wiley Online Library
The pharmacological management of diabetes in older people is complex and challenging.
It requires a comprehensive understanding of the individual beyond the diabetes itself …

The effect of dopamine agonists on metabolic variables in adults with type 2 diabetes: a systematic review with meta analysis and trial sequential analysis of …

IB Andersen, M Andreassen… - Diabetes, Obesity and …, 2021 - Wiley Online Library
Aim To assess the metabolic effects of dopamine agonists compared with placebo in
randomized controlled trials (RCTs) including adults with type 2 diabetes. Materials and …

Should side effects influence the selection of antidiabetic therapies in type 2 diabetes?

G Grunberger - Current Diabetes Reports, 2017 - Springer
Abstract Purpose of Review There are currently over 40 different drugs in 12 distinct classes
approved in the USA to treat patients with type 2 diabetes mellitus. This review summarizes …

Bromocriptine-QR therapy for the management of type 2 diabetes mellitus: developmental basis and therapeutic profile summary

P Raskin, AH Cincotta - Expert review of endocrinology & …, 2016 - Taylor & Francis
An extended series of studies indicate that endogenous phase shifts in circadian neuronal
input signaling to the biological clock system centered within the hypothalamic …

Impact of bromocriptine-QR therapy on cardiovascular outcomes in type 2 diabetes mellitus subjects on metformin

B Chamarthi, M Ezrokhi, D Rutty… - Postgraduate …, 2016 - Taylor & Francis
Objectives: Type 2 diabetes mellitus (T2DM) is associated with a substantially increased risk
of cardiovascular disease (CVD). Bromocriptine-QR (B-QR), a quick release sympatholytic …