Curcumin-Incorporated Biomaterials: In silico and in vitro evaluation of biological potentials
Curcumin (diferuloylmethane) is the main constituent extracted from turmeric. This
polyphenol is a non-toxic, potent compound with anticancer, anti-inflammatory, antibacterial …
polyphenol is a non-toxic, potent compound with anticancer, anti-inflammatory, antibacterial …
Unmasking the deceptive nature of cancer stem cells: The role of cd133 in revealing their secrets
J Pospieszna, H Dams-Kozlowska, W Udomsak… - International Journal of …, 2023 - mdpi.com
Cancer remains a leading cause of death globally, and its complexity poses a significant
challenge to effective treatment. Cancer stem cells and their markers have become key …
challenge to effective treatment. Cancer stem cells and their markers have become key …
[HTML][HTML] How Do ROS Induce NETosis? Oxidative DNA Damage, DNA Repair, and Chromatin Decondensation
D Azzouz, N Palaniyar - Biomolecules, 2024 - mdpi.com
Neutrophil extracellular traps (NETs) are intricate, DNA-based, web-like structures adorned
with cytotoxic proteins. They play a crucial role in antimicrobial defense but are also …
with cytotoxic proteins. They play a crucial role in antimicrobial defense but are also …
The dual role of autophagy in suppressing and promoting hepatocellular carcinoma
The 5-year survival rate for hepatocellular carcinoma (HCC), a deadly form of liver cancer, is
quite low. Although drug therapy is successful, patients with advanced liver cancer …
quite low. Although drug therapy is successful, patients with advanced liver cancer …
Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in …
H Fang, X Chen, Y Zhong, S Wu, Q Ke… - Frontiers in …, 2024 - frontiersin.org
Background Hepatocellular carcinoma (HCC) poses a significant global health challenge
due to its poor prognosis and limited therapeutic modalities. Anoikis and ErbB signaling …
due to its poor prognosis and limited therapeutic modalities. Anoikis and ErbB signaling …
MicroRNA as key players in hepatocellular carcinoma: insights into their role in metastasis
MJ Saadh, QM Hussain, TS Alazzawi, AA Fahdil… - Biochemical …, 2024 - Springer
Liver cancer or hepatocellular carcinoma (HCC) remains the most common cancer in global
epidemiology. Both the frequency and fatality of this malignancy have shown an upward …
epidemiology. Both the frequency and fatality of this malignancy have shown an upward …
Chitosan‐coated nanoparticles in innovative cancer bio‐medicine
In the recent decade, nanoparticles (NPs) have had enormous implications in cancer
biomedicine, including research, diagnosis, and therapy. However, their broad application …
biomedicine, including research, diagnosis, and therapy. However, their broad application …
[HTML][HTML] Deciphering the multifaceted role of microRNAs in hepatocellular carcinoma: Integrating literature review and bioinformatics analysis for therapeutic insights
Hepatocellular carcinoma (HCC) poses a significant global health challenge, necessitating
innovative therapeutic strategies. MicroRNAs (miRNAs) have emerged as pivotal regulators …
innovative therapeutic strategies. MicroRNAs (miRNAs) have emerged as pivotal regulators …
[HTML][HTML] Pharmacologically inducing anoikis offers novel therapeutic opportunities in hepatocellular carcinoma
Y Wang, JS Fleishman, J Wang, J Chen, L Zhao… - Biomedicine & …, 2024 - Elsevier
Tumor metastasis occurs in hepatocellular carcinoma (HCC), leading to tumor progression
and therapeutic failure. Anoikis is a matrix detachment-induced apoptosis, also known as …
and therapeutic failure. Anoikis is a matrix detachment-induced apoptosis, also known as …
[HTML][HTML] P53/NANOG balance; the leading switch between poorly to well differentiated status in liver cancer cells
Enforcing a well-differentiated state on cells requires tumor suppressor p53 activation as a
key player in apoptosis induction and well differentiation. In addition, recent investigations …
key player in apoptosis induction and well differentiation. In addition, recent investigations …