Nonsense-mediated mRNA decay (NMD) is one of the best characterized and most
evolutionarily conserved cellular quality control mechanisms. Although NMD was first found …

Abstract mRNA surveillance pathways are essential for accurate gene expression and to
maintain translation homeostasis, ensuring the production of fully functional proteins. Future …

Nonsense-mediated mRNA decay (NMD) is probably the best characterized eukaryotic RNA
degradation pathway. Through intricate steps, a set of NMD factors recognize and degrade …

Although microRNAs (miRNAs), other non-coding RNAs (ncRNAs)(eg lncRNAs,
pseudogenes and circRNAs) and competing endogenous RNAs (ceRNAs) have been …

Nonsense-mediated mRNA decay (NMD) is an mRNA quality-control mechanism that
typifies all eukaryotes examined to date. NMD surveys newly synthesized mRNAs and …

Regnase-1 and Roquin are RNA binding proteins essential for degradation of inflammation-
related mRNAs and maintenance of immune homeostasis. However, their mechanistic …

Throughout their lifetimes, messenger RNAs (mRNAs) associate with proteins to form
ribonucleoproteins (mRNPs). Since the discovery of the first mRNP component more than 40 …

Nonsense-mediated mRNA decay (NMD) is arguably the best-studied eukaryotic
messenger RNA (mRNA) surveillance pathway, yet fundamental questions concerning the …

The Nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs
harboring premature termination codons (PTCs) but also regulates the abundance of a large …

Nonsense-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism that
monitors cytoplasmic mRNA translation and targets mRNAs undergoing premature …