Breast cancer, specifically metastatic breast, is a leading cause of morbidity and mortality in
women. This is mainly due to relapse and reoccurrence of tumor. The primary reason for …

Theranostic nanoplatforms with integrated diagnostic and therapeutic functions, aiming at
imaging‐guided therapy to improve treatment planning, as well as combination therapy to …

Hyaluronic acid-ceramide (HA-CE)-based self-assembled nanoparticles were developed for
intravenous docetaxel (DCT) delivery. In this study, physicochemical properties, cellular …

Background Targeting drugs to their sites of action to overcome the systemic side effects
associated with most antineoplastic agents is still a major challenge in pharmaceutical …

Cancer immunotherapy is a therapeutic strategy to inhibit tumor growth and metastasis by
intervening in the immune response process. Strategies applied to cancer immunotherapy …

The main purpose of this study was to investigate the potential of self-nano-emulsifying drug
delivery system (SNEDDS) in improving the bioavailability of docetaxel (DCT) and its …

Nanoxel-PM™, docetaxel-loaded methoxy-poly (ethylene glycol)-block-poly (d, l-
lactide)(mPEG-PDLLA) micellar formulation was prepared in an effort to develop alternative …

Importance in the field: Activated cells metabolize albumin to cover their increased need for
amino acids and energy. In inflamed, diseased and malignant tissue, extravasation of …

Rectal drug delivery is an effective alternative to oral and parenteral treatments. This route
allows for both local and systemic drug therapy. Traditional rectal dosage formulations have …

The purpose of this study is to evaluate in vivo antitumor efficacy and subacute toxicity of
docetaxel (DTX) prodrug comprising a conjugate between DTX and low molecular weight …