Vascular endothelial growth factor (VEGF) is a key regulator of physiological angiogenesis
during embryogenesis, skeletal growth and reproductive functions. VEGF has also been …

Cardiac hypertrophy is an adaptive response to physiological and pathological overload. In
response to the overload, individual cardiac myocytes become mechanically stretched and …

INTRODUCTION All body cells rely on blood vessels (BVs) for the provision of oxygen and
other blood-borne substances and, in certain settings, also for the provision of endothelial …

In a cell-free approach to regenerative therapeutics, transient application of paracrine factors
in vivo could be used to alter the behavior and fate of progenitor cells to achieve sustained …

Blood vessels constitute the first organ in the embryo and form the largest network in our
body but, sadly, are also often deadly. When dysregulated, the formation of new blood …

The family of fibroblast growth factors (FGFs) regulates a plethora of developmental
processes, including brain patterning, branching morphogenesis and limb development …

Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and
an angiogenic inducer in a variety of in vivo models. Hypoxia has been shown to be a major …

It takes two to make blood vessels—endothelial cells and pericytes. While the endothelial
cells are the better characterized of the two, pericytes are now coming into focus as …

Here, we describe that microenvironmental IL-1β and, to a lesser extent, IL-1α are required
for in vivo angiogenesis and invasiveness of different tumor cells. In IL-1β knockout (KO) …

Adult neovascularization relies on the recruitment of circulating cells, but their angiogenic
roles and recruitment mechanisms are unclear. We show that the endothelial growth factor …