Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Background: Patients with substantive bleeding usually require transfusion and/or (re-)
operation. Red blood cell (RBC) transfusion is independently associated with a greater risk …

The world-wide impact of traumatic injury and associated hemorrhage on human health and
well-being cannot be overstated. Twelve percent of the global disease burden is the result of …

Background: Patients with severe traumatic injuries often present with coagulopathy and
require massive transfusion. The risk of death from hemorrhagic shock increases in this …

Background: Red blood cell (RBC) transfusions are common in intensive care unit, trauma,
and surgical patients. However, the hematocrit that should be maintained in any particular …

Objective: Our objective was to quantify incremental risk associated with transfusion of
packed red blood cells and other blood components on morbidity after coronary artery …

Objective: To develop a clinical practice guideline for red blood cell transfusion in adult
trauma and critical care. Design: Meetings, teleconferences and electronic-based …

After several decades of intensive efforts, safe injectable preparations capable of effectively
delivering O2 to tissues and removing CO2, ie, so-called blood substitutes, appear to be …

The acute blood transfusion reactions are responsible for causing most serious adverse
events. Awareness about various clinical features of acute and delayed transfusion …

Massive transfusion (MT) is a lifesaving treatment of hemorrhagic shock, but can be
associated with significant complications. The lethal triad of acidosis, hypothermia, and …