Mast cells (MCs) are portions of the innate and adaptive immune system derived from bone
marrow (BM) progenitors that are rich in cytoplasmic granules. MC maturation, phenotype …

Childhood asthma represents a heterogeneous challenging disease, in particular in its
severe forms. The identification of different asthma phenotypes has stimulated research in …

Background Real‐world evidence is sparse on the benefits of allergen immunotherapy [AIT;
subcutaneous/sublingual immunotherapy (SCIT/SLIT)], the only disease‐modifying …

Epidemiologic, pathophysiologic, and clinical evidences recently revealed the link between
upper and lower airways, changing the global pathogenic view of respiratory allergy. The …

Background Recently, academic studies suggest that global growth of airway allergic
disease has a close association with dietary changes including reduced consumption of …

Evaluating the degree of disease control is pivotal when assessing a patient with asthma.
Asthma control is defined as the degree to which manifestations of the disease are reduced …

In addition to nasal symptoms, patients with allergic rhinitis (AR) often experience mental
and psychological disorders such as depression. Depression not only makes the treatment …

Allergic rhinitis (AR) is a type I hypersensitivity immune response and is a common chronic
allergic respiratory disorder characterized by one or more nasal symptoms. Despite many …

Allergic rhinitis (AR) is a chronic upper airway immune‐inflammation response mediated by
immunoglobulin E (IgE) to allergens and can seriously affect the quality of life and work …

Mast cells (MCs) are physiologically activated by binding of stem cell factor (SCF) to the
extracellular domains of the Kit receptor. This binding increases the proliferation and …