Extractive distillation processes enable the separation of non-ideal mixtures, including
minimum or maximum boiling azeotropes and low relative volatility mixtures. Unlike …

How do accidents and disasters occur? How has knowledge of accident processes
evolved? A significant improvement in safety has occurred during the past century, with the …

This work presents the optimal synthesis and design of a rigorous catalytic distillation (CD)
column that explicitly considers the multiscale and multiphase nature of this intensification …

Accurate prediction of ethane and ethylene compositions in binary distillation columns is
critical for optimizing industrial separation processes. Traditional modeling approaches often …

In this paper we study the design and optimization of heat-integrated distillation columns
(HIDiC) using a constrained Boltzmann-based estimation of distribution algorithm. The total …

The rate-based model for distillation computes mass and heat transfer rates, allowing better
predictions of the performance of the columns. Nevertheless, one of the fundamental issues …

Nowadays, chemical processes are projected to obtain their best performance in energy and
water consumption, pollutant emissions and total annual costs, while still meeting quality of …

The design of chemical processes has to consider the delivery of products with high quality,
minimum energy requirements and minimum impact to the environment. In order to design …

The economic, energetic, and environmental performance of heat-integrated distillation
columns used to separate close-boiling mixtures with variable feed composition is …

This PhD thesis presents the development and application of new optimization models and
algorithms for the solution of relevant Mixed Integer Nonlinear Programming (MINLP) and …