Imaging genetics offers the possibility of detecting associations between genotype and brain
structure as well as function, with effect sizes potentially exceeding correlations between …

Large-scale comparisons of patients and healthy controls have unearthed genetic risk
factors associated with a range of neurological and psychiatric illnesses. Meanwhile, brain …

Recent longitudinal studies in youth have reported MRI correlates of prospective anxiety
symptoms during adolescence, a vulnerable period for the onset of anxiety disorders …

Background Accumulating studies have found structural and functional abnormalities of the
striatum in bipolar disorder (BD) and major depressive disorder (MDD). However, changes …

This study examines the effects of puberty and sex on the intrinsic functional connectivity
(iFC) of brain networks, with a focus on the default-mode network (DMN). Consistently …

There is a gap in knowledge regarding the polygenic underpinnings of brain anomalies
observed in youth bipolar disorder (BD). This study examined the association of a polygenic …

The notion that healthy brain function emerges from coordinated neural activity constrained
by the brain's network of anatomical connections—ie, the connectome—suggests that …

Background Schizophrenia (SZ) and bipolar disorder (BD) share substantial
neurodevelopmental components affecting brain maturation and architecture. This …

Background Inflammation and immunological alterations, such as T-cell and cytokine
changes, are implicated in bipolar disorder (BD), with some evidence linking them to brain …

Alterations in the microarchitecture of the posterior cingulum (PC), a white matter tract
proximal to the hippocampus that facilitates communication between the entorhinal and …