Clinical trials with mesenchymal stem cells: an update

T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …

Mesenchymal stem cells in fibrotic disease

E El Agha, R Kramann, RK Schneider, X Li, W Seeger… - Cell stem cell, 2017 - cell.com
Fibrosis is associated with organ failure and high mortality and is commonly characterized
by aberrant myofibroblast accumulation. Investigating the cellular origin of myofibroblasts in …

Stem cells and regenerative medicine: myth or reality of the 21th century

JF Stoltz, N de Isla, YP Li, D Bensoussan… - Stem cells …, 2015 - Wiley Online Library
Since the 1960s and the therapeutic use of hematopoietic stem cells of bone marrow origin,
there has been an increasing interest in the study of undifferentiated progenitors that have …

Stem cells and cell therapies in lung biology and lung diseases

DJ Weiss, I Bertoncello, Z Borok, C Kim… - Proceedings of the …, 2011 - atsjournals.org
EXECUTIVE SUMMARY The University of Vermont College of Medicine and the Vermont
Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the …

Mesenchymal stem cell‐based therapy: a new paradigm in regenerative medicine

NK Satija, VK Singh, YK Verma, P Gupta… - Journal of cellular …, 2009 - Wiley Online Library
Introduction• Mesenchymal stem cells and its characteristics• Experimental/preclinical MSC‐
based studies–MSC transplantation–Genetically modified MSC‐based therapy–MSC‐based …

CD271+ Bone Marrow Mesenchymal Stem Cells May Provide a Niche for Dormant Mycobacterium tuberculosis

B Das, SS Kashino, I Pulu, D Kalita, V Swami… - Science translational …, 2013 - science.org
Mycobacterium tuberculosis (Mtb) can persist in hostile intracellular microenvironments
evading immune cells and drug treatment. However, the protective cellular niches where …

The gap between the physiological and therapeutic roles of mesenchymal stem cells

U Galderisi, A Giordano - Medicinal research reviews, 2014 - Wiley Online Library
Several investigators have cultivated marrow stromal cells and have identified a population
of mesenchymal stem cells (MSCs). These cells expand extensively in vitro and exhibit …

Concise review: Adult salivary gland stem cells and a potential therapy for xerostomia

S Pringle, R Van Os, RP Coppes - Stem cells, 2013 - academic.oup.com
The ability to speak, swallow, masticate, taste food, and maintain a healthy oral cavity is
heavily reliant on the presence of saliva, the hugely important effect of which on our …

Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo

G Bilousova, DH Jun, KB King, S De Langhe… - Stem …, 2011 - academic.oup.com
Reprogramming somatic cells into an ESC-like state, or induced pluripotent stem (iPS) cells,
has emerged as a promising new venue for customized cell therapies. In this study, we …

Regeneration of the lung: Lung stem cells and the development of lung mimicking devices

KAA Schilders, E Eenjes, S van Riet, AA Poot… - Respiratory …, 2016 - Springer
Inspired by the increasing burden of lung associated diseases in society and an growing
demand to accommodate patients, great efforts by the scientific community produce an …