Disinfectants and antiseptics: mechanisms of action and resistance

JY Maillard, M Pascoe - Nature Reviews Microbiology, 2024 - nature.com
Chemical biocides are used for the prevention and control of infection in health care,
targeted home hygiene or controlling microbial contamination for various industrial …

[HTML][HTML] Prevalence of ESKAPE pathogens in the environment: Antibiotic resistance status, community-acquired infection and risk to human health

J Denissen, B Reyneke, M Waso-Reyneke… - International journal of …, 2022 - Elsevier
Abstract The ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp.) …

[HTML][HTML] Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria

KL Wyres, KE Holt - Current opinion in microbiology, 2018 - Elsevier
Klebsiella pneumoniae is an opportunistic bacterial pathogen known for its high frequency
and diversity of antimicrobial resistance (AMR) genes. In addition to being a significant …

General Overview of Klebsiella pneumonia: Epidemiology and the Role of Siderophores in Its Pathogenicity

R Abbas, M Chakkour, H Zein El Dine, EF Obaseki… - Biology, 2024 - mdpi.com
Simple Summary Numerous diseases, such as liver abscesses, bacteremias, pneumonia,
and urinary tract infections, are caused by Klebsiella pneumonia (K. pneumonia) …

Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae

KL Wyres, RR Wick, LM Judd, R Froumine… - PLoS …, 2019 - journals.plos.org
Klebsiella pneumoniae has emerged as an important cause of two distinct public health
threats: multi-drug resistant (MDR) healthcare-associated infections and drug susceptible …

Identification of Klebsiella capsule synthesis loci from whole genome data

KL Wyres, RR Wick, C Gorrie, A Jenney… - Microbial …, 2016 - microbiologyresearch.org
Klebsiella pneumoniae is a growing cause of healthcare-associated infections for which
multi-drug resistance is a concern. Its polysaccharide capsule is a major virulence …

Metal resistance and its association with antibiotic resistance

C Pal, K Asiani, S Arya, C Rensing, DJ Stekel… - Advances in microbial …, 2017 - Elsevier
Antibiotic resistance is recognised as a major global threat to public health by the World
Health Organization. Currently, several hundred thousand deaths yearly can be attributed to …

Mechanisms of increased resistance to chlorhexidine and cross-resistance to colistin following exposure of Klebsiella pneumoniae clinical isolates to chlorhexidine

ME Wand, LJ Bock, LC Bonney… - Antimicrobial agents and …, 2017 - journals.asm.org
Klebsiella pneumoniae is an opportunistic pathogen that is often difficult to treat due to its
multidrug resistance (MDR). We have previously shown that K. pneumoniae strains are able …

Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations

MMC Lam, RR Wick, KL Wyres… - Microbial …, 2018 - microbiologyresearch.org
Mobile genetic elements (MGEs) that frequently transfer within and between bacterial
species play a critical role in bacterial evolution, and often carry key accessory genes that …

Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination

MMC Lam, KL Wyres, S Duchêne, RR Wick… - Nature …, 2018 - nature.com
Severe liver abscess infections caused by hypervirulent clonal-group CG23 Klebsiella
pneumoniae have been increasingly reported since the mid-1980s. Strains typically possess …