Single-Cell Technologies for Studying the Evolution and Function of Mitochondrial DNA Heteroplasmy in Cancer

S Boscenco, EM Cumming, M Kim… - Annual Review of …, 2024 - annualreviews.org
The mitochondrial genome, which encodes genes essential for respiration and cellular
homeostasis, is the target of abundant and highly diverse somatic alterations in cancers …

[HTML][HTML] Diagnosis and Management of Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes Syndrome

JH Na, YM Lee - Biomolecules, 2024 - mdpi.com
Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome
is a complex mitochondrial disorder characterized by a wide range of systemic …

Unraveling bidirectional evolution of unstable mitochondrial DNA mutations in hepatocellular carcinoma at single-cell resolution

K Zhou, Z Wang, W Guo, F **e, Q Yuan, S Guo… - Hepatology, 2024 - journals.lww.com
Impact of COVID‐19 pandemic on HCV care cascade in Rwanda: Ecological study from July
2019 to June 2021 Page 1 Unraveling bidirectional evolution of unstable mitochondrial DNA …

Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease

Z Zhu, G Luan, S Wu, Y Song, S Shen, K Wu… - Journal of Translational …, 2025 - Springer
Abstract Background and Objective Mitochondria are crucial to the function of renal tubular
cells, and their dynamic perturbation in many aspects is an important mechanism of diabetic …

Artifacts in single-cell mitochondrial DNA mutation analyses misinform phylogenetic inference

CA Lareau, MS Chapman, L Penter, T Nawy, D Pe'er… - bioRxiv, 2024 - biorxiv.org
Sequencing mitochondrial DNA (mtDNA) variants from single cells has resolved clonality
and lineage in native human samples and clinical specimens. Prior work established that …

Probiotic Limosilactobacillus reuteri DSM 17938 Alleviates Acute Liver Injury by Activating the AMPK Signaling via Gut Microbiota–Derived Propionate

Y Zhao, W **e, J Duan, F Li - Probiotics and Antimicrobial Proteins, 2025 - Springer
Limosilactobacillus reuteri DSM 17938 (L. reuteri DSM 17938) was one of the most widely
used probiotics in humans for gastrointestinal disorders, but few studies have investigated …

[HTML][HTML] Deciphering the Complexities of Adult Human Steady State and Stress-Induced Hematopoiesis: Progress and Challenges

SM Watt, MG Roubelakis - International Journal of Molecular …, 2025 - pmc.ncbi.nlm.nih.gov
Human hematopoietic stem cells (HSCs) have traditionally been viewed as self-renewing,
multipotent cells with enormous potential in sustaining essential steady state blood and …

Genomic synergy in food traceability: enhancing global food safety and security

JT Liberty - Ecological Genetics and Genomics, 2025 - Elsevier
The global food system faces unprecedented challenges from foodborne diseases,
contamination, fraud, and climate change-induced disruptions, threatening public health and …

[HTML][HTML] Single-Cell Mitochondrial DNA Sequencing: Methodologies and Applications

G Zhou, Z Gu, J Xu - Mitochondrial Communications, 2024 - Elsevier
Mitochondria play a pivotal role in cellular energetics, metabolism, and various regulatory
processes. Their dysregulation is implicated in numerous diseases. Traditional population …

The first complete mitochondrial genome of Loimia arborea (Polychaeta: Terebellidae) and phylogenetic analysis

X Xu, C Luo, Y Mu - Mitochondrial DNA Part B, 2024 - Taylor & Francis
In order to understand the molecular insights within the Terebellida, the complete
mitochondrial genome of Loimia arborea was sequenced. The mitochondrial genome is …