A systematic analysis of all naturally-occurring glycosylated bacterial secondary metabolites
reported in the scientific literature up through early 2013 is presented. This comprehensive …

In this review, we address recent advances made in pathway engineering, directed
evolution, and systems/synthetic biology approaches employed in the production and …

Naturally occurring (native) sugars and carbohydrates contain numerous hydroxyl groups of
similar reactivity,. Chemists, therefore, rely typically on laborious, multi-step protecting-group …

Natural flavonoids, especially in their glycosylated forms, are the most abundant phenolic
compounds found in plants, fruit, and vegetables. They exhibit a large variety of beneficial …

Glycosylation reactions mainly catalyzed by glycosyltransferases (Gts) occur almost
everywhere in the biosphere, and always play crucial roles in vital processes. In order to …

Glycosyltransferases are effective enzymes for glycosylating natural products (NPs), and
some of them have the unusual property of being exceedingly promiscuous catalytically …

A set of model nucleophiles of gradually changing nucleophilicity is used to probe the
glycosylation reaction mechanism. Glycosylations of ethanol-based acceptors, bearing …

Covering: up to the end of May 2011 Glyco (randomization/diversification) is a term that
encompasses strategies to diversify a core drug scaffold via enzymatic glycosylation to …

In the presence of a diarylborinic acid catalyst, glycosyl methanesulfonates engage in regio-
and stereoselective couplings with partially protected pyranoside and furanoside acceptors …

Flavonoids, terpenoids, and polyketides are structurally diverse secondary metabolites used
widely as pharmaceuticals and nutraceuticals. Most of these molecules exist in nature as …