Mesenchymal stem cell transplantation is undergoing extensive evaluation as a cellular
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …

Chronic myeloid leukemia (CML) is caused by BCRABL1 in a cell with the biological
potential, intrinsic or acquired, to cause leukemia. This cell is commonly termed the CML …

Extracellular vesicles (EVs) are membrane-enveloped nanoscale particles that carry various
bioactive signaling molecules secreted by cells. Their biological roles depend on the …

Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm driven by BCR-
ABL1 oncoprotein, which plays a pivotal role in CML pathology, diagnosis, and treatment as …

In industrialized countries, cancer is the second leading cause of death after cardiovascular
disease. Most cancer patients die because of metastases, which consist of the self …

Epithelial–mesenchymal transition (EMT) causes epithelial cells to lose their polarity and
adhesion property, and endows them with migratory and invasive properties to enable them …

Aging is characterized by a progressive loss of physiological integrity, while cancer
represents one of the primary pathological factors that severely threaten human lifespan and …

Non-small cell lung cancer (NSCLC) remains the leading cause of cancer-related deaths
worldwide. The majority of patients are diagnosed in advanced disease stage. Bone …

Background Multiple myeloma (MM) is a clonal plasma cell malignancy associated with
osteolytic bone disease. Recently, the role of MM-derived exosomes in the …

Objectives Traditional cancer therapy and regular immunotherapy are ineffective for treating
triple‐negative breast cancer (TNBC) patients. Recently, chimeric antigen receptor …