The contribution of inflammation to bone loss is well documented in arthritis and other
diseases with an emphasis on how inflammatory cytokines promote osteoclastogenesis …

Bone regeneration is a complex and well‐coordinated process that involves crosstalk
between immune cells and resident cells in the injury site. Transplantation of mesenchymal …

Abstract Mesenchymal Stem Cells (MSCs) are effective therapeutic agents enhancing the
repair of injured tissues mostly through their paracrine activity. Increasing evidences show …

Since the reconstruction of large bone defects remains a challenge, knowledge about the
biology of bone healing is desirable to develop novel strategies for improving the treatment …

Transplantation of mesenchymal stem cells (MSCs) has been considered an effective
therapeutic treatment for a variety of diseases including bone fracture. However, there are …

Despite its natural healing potential, bone is unable to regenerate sufficient tissue within
critical‐sized defects, resulting in a non‐union of bone ends. As a consequence …

During the past decade, mesenchymal stem cells (MSCs) have made their mark as a
potential weapon in regenerative medicine. Since their first isolation by Friedenstein in the …

Fractures are the most common large organ trauma in humans. The initial inflammatory
response promotes bone healing during the initial post-fracture phase, but chronic and …

The therapeutic effects of mesenchymal stem cells (MSCs)–material constructs mainly come
from the secretion of trophic factors from MSCs, especially the immunomodulatory and …

Recent years have witnessed the emergence of a considerable amount of data pertaining to
the application of bone marrow mesenchymal stem cells (MSCs) in promoting angiogenesis …