In this review we compare and discuss results of compounds already reported as anticancer
agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds …

Simple Summary Organometallics, such as copper compounds, are cancer
chemotherapeutics used alone or in combination with other drugs. One small group of …

Cancer is a complex issue and, even though the prevention basics and therapy have been
implemented, it is still the second leading death cause worldwide. With the hope to discover …

Introduction Cancer has been identified as one of the leading causes of death worldwide.
The biological target of some anticancer agents is topoisomerase I, an enzyme involved in …

Topoisomerase I (Topo I) is a nuclear enzyme engaged in adjustment of DNA topological
structure during cell cycle by cleaving and reannealing one of the two strands of the DNA …

Vanadium compounds were studied during recent years to be considered as a
representative of a new class of nonplatinum metal antitumor agents in combination to its …

Microelements such as copper are essential and involved in various biological processes
and under strict homeostatic regulation. Compared to healthy individuals, cancer patients …

A series of new 3d metal complexes with 5-chloro-quinolin-8-ol (ClQ),[Mn (ClQ) 2](1),[Fe
(ClQ) 3](2),[Co (ClQ) 2 (H 2 O) 2](3),[Ni (ClQ) 2 (H 2 O) 2](4),[Cu (ClQ) 2](5),[Zn (ClQ) 2 (H 2 …

Herein we discuss five ruthenium (II) complexes with good cytotoxicity against cancer cells.
These complexes are named [Ru (tzdt)(bipy)(dppb)] PF6 (1),[Ru (mmi)(bipy)(dppb)] PF6 …

N-Heterocyclic carbene (NHC) metal complexes are attracting scientists' interest as an
alluring class of metallodrugs. Indeed, the versatile functionalization of NHC ligands makes …