Linking inflammation, aberrant glutamate-dopamine interaction, and post-synaptic changes: translational relevance for schizophrenia and antipsychotic treatment: a …

A de Bartolomeis, A Barone, L Vellucci, B Mazza… - Molecular …, 2022 - Springer
Evidence from clinical, preclinical, and post-mortem studies supports the
inflammatory/immune hypothesis of schizophrenia pathogenesis. Less evident is the link …

Advanced EEG-based learning approaches to predict schizophrenia: Promises and pitfalls

C Barros, CA Silva, AP Pinheiro - Artificial intelligence in medicine, 2021 - Elsevier
The complexity and heterogeneity of schizophrenia symptoms challenge an objective
diagnosis, which is typically based on behavioral and clinical manifestations. Moreover, the …

A systematic review of multimodal brain age studies: Uncovering a divergence between model accuracy and utility

RJ Jirsaraie, AJ Gorelik, MM Gatavins, DA Engemann… - Patterns, 2023 - cell.com
Brain aging is a complex, multifaceted process that can be challenging to model in ways that
are accurate and clinically useful. One of the most common approaches has been to apply …

[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

[HTML][HTML] Hidden role of gut microbiome dysbiosis in schizophrenia: Antipsychotics or psychobiotics as therapeutics?

N Munawar, K Ahsan, K Muhammad, A Ahmad… - International journal of …, 2021 - mdpi.com
Schizophrenia is a chronic, heterogeneous neurodevelopmental disorder that has complex
symptoms and uncertain etiology. Mounting evidence indicates the involvement of genetics …

Cytokine imbalance in schizophrenia. From research to clinic: potential implications for treatment

M Reale, E Costantini, NH Greig - Frontiers in psychiatry, 2021 - frontiersin.org
Cytokines are one of the most important components of the immune system. They
orchestrate the brain's response to infectious and other exogenous insults and are crucial …

Cytokines dysregulation in schizophrenia: a systematic review of psychoneuroimmune relationship

D Rodrigues-Amorim, T Rivera-Baltanas, C Spuch… - Schizophrenia …, 2018 - Elsevier
Introduction: Schizophrenia is a multifactorial psychiatric disease with complex interactions
among the brain and the immune system. A psycho-immune relationship underling …

Subty** schizophrenia patients based on patterns of structural brain alterations

Y **ao, W Liao, Z Long, B Tao, Q Zhao… - Schizophrenia …, 2022 - academic.oup.com
Schizophrenia is a complex and heterogeneous syndrome. Whether quantitative imaging
biomarkers can identify discrete subgroups of patients as might be used to foster …

EEG microstates as biomarker for psychosis in ultra-high-risk patients

R de Bock, AJ Mackintosh, F Maier, S Borgwardt… - Translational …, 2020 - nature.com
Resting-state EEG microstates are brief (50–100 ms) periods, in which the spatial
configuration of scalp global field power remains quasi-stable before rapidly shifting to …

Constructing the immune signature of schizophrenia for clinical use and research; an integrative review translating descriptives into diagnostics

RA Kroken, IE Sommer, VM Steen, I Dieset… - Frontiers in …, 2019 - frontiersin.org
Schizophrenia is considered a syndrome comprised by several disease phenotypes,
covering a range of underlying pathologies. One of these disease mechanisms seems to …